Protein Alignment mthl5 and adgre14

DIOPT Version :9

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_021330419.1
• Gene: adgre14 / 108182849
• ZFINID: ZDB-GENE-131120-49
• Length: 505
• Species: Danio rerio
• Alignment Length: 390
• Identity: 81/390 - (20%)
• Similarity: 140/390 - (35%)
• Gaps: 116/390 - (29%)

  Fly   160 EEDIAGSLEPLYHDYDKGLY----------------CIDKATSSTGEENVLFANICLARKEIKWS 208
            |.|.:||...:|.:..|.:.                |:..:|         ||.|...|.....|
Zfish   158 EFDPSGSFSCVYWNISKWIVDGCSVLNTNRSFTVCSCVHLST---------FALIMQTRSHPPES 213

  Fly   209 DSNFLLRKILNPIFHGISLVILLVIAIIYFILPTLSRDLVG-----NIVTTIAMCLMVSQAADLV 268
            ||   |..:||        |:.:::.:::|.|..|:.....     |.|..|.:|:.: ..|.|:
Zfish   214 DS---LLNVLN--------VVCVIVGLLFFSLALLTFTRCQWSPGVNNVARINICISL-LLAHLL 266

  Fly   269 RIFTELTSHVSFIVADIILC--FSLLAAFFWLNSFGFYIWKTFRSRNVFLRVTD----------- 320
            .:.|:  ..:|.|....:||  .|.|..|.:|:.|   :|....:..:|:.|.:
Zfish   267 FLLTQ--QFLSLIRRQKVLCMLISGLLHFLFLSGF---VWMFIEAVLLFICVKNLSQISSQMKNV 326

  Fly   321 -GRKYCYYSAYAWGCTATMAALAVFAHFFLDAESYKQEHMVGEQETIGWLGICIFFAPIACTILV 384
             ..|......||........:.||..:.:...:.:.|.|.       |:  |..|..|:...|.:
Zfish   327 LRNKLLCVIGYAVALVVVSISAAVVPNGYGSEKCWIQMHK-------GF--IWSFLGPVTIIIAL 382

  Fly   385 NIFFYVTTRKLINRRTVYGRIAHKLKANF---------------IMFSLM--LLVMSIAWL--FL 430
            |:..:::             |...||:.|               :||..:  .:|:..:|:  |.
Zfish   383 NVILFIS-------------IGFSLKSAFKKLNADVSQLNQTKIVMFKTLAQFVVLGCSWILGFF 434

  Fly   431 IMSWLQMEGLLYAHIVVNALQ-TPLLLYICVL----RQRHVTFLLKKTCCYN--EPPSANDWGDE 488
            ..|...:|.|.   :::|:.| |.:.|..|||    ||.:....   |..|:  :|.:.| |..|
Zfish   435 TNSSKVLEILF---LILNSQQGTFIFLIYCVLNKGIRQEYRKLF---TSLYSGLKPKNFN-WSSE 492

  Fly   489  488
            Zfish   493  492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	52/276 (19%)
adgre14	XP_021330419.1	GPS	167..205	CDD:197639	7/46 (15%)
		7tm_GPCRs	214..476	CDD:333717	62/306 (20%)
		TM helix 1	217..241	CDD:320095	6/31 (19%)
		TM helix 2	250..271	CDD:320095	5/21 (24%)
		TM helix 3	285..307	CDD:320095	6/24 (25%)
		TM helix 4	331..347	CDD:320095	2/15 (13%)
		TM helix 5	365..388	CDD:320095	7/31 (23%)
		TM helix 6	412..435	CDD:320095	5/22 (23%)
		TM helix 7	439..464	CDD:320095	8/27 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810