Protein Alignment mthl5 and adgrf3a

DIOPT Version :10

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_021322955.3
• Gene: adgrf3a / 101886922
• ZFINID: ZDB-GENE-131121-607
• Length: 997
• Species: Danio rerio
• Alignment Length: 293
• Identity: 66/293 - (22%)
• Similarity: 114/293 - (38%)
• Gaps: 72/293 - (24%)

  Fly   224 GISLVILLVIAII-YFILPTLSRDLVGNI----VTTIAMCLMVSQAADLVRIFTELTSHVSFI-- 281
            |||::.||...|| ..:...:.:..:.|.    :..|::||:::....|.      ||....|
Zfish   709 GISILSLLACLIIKVLVWDAVVKSPISNFRHVALFNISLCLLLAHCMFLT------TSKPESIPP 767

  Fly   282 ----VADIILCFSLLAAFFWLNSFGF-------YIWKTFRSRNVF--LRVTDGRKYCYYSAYAWG 333
                :..:|..|..||.|||:....|       |::...| :.||  |.:|.|          :.
Zfish   768 NWCSILTLIKHFFFLAVFFWMLCLSFVLLHQMIYVFDRLR-KKVFLGLSITVG----------YA 821

  Fly   334 CTATMAALAVFAHFFLDAESYKQEHMVGE--QETIGWL--------GICIFFAPIACTILVNIFF 388
            | ..:|....:..|...||        ||  .::..||        .|..|..||...:.||:|.
Zfish   822 C-PIIAVAVTYISFNNGAE--------GEYYSKSTCWLTYKGTLKGSIFAFIIPIGAIVFVNLFT 877

  Fly   389 YVTTRKLINRRTVYGRIAHKLK--ANFIMFSLMLL--VMSIAWL--FLIMS-------WLQMEGL 440
            .......|...::....|...|  |..::.:::.|  |:.::|:  |.::.       |..:  :
Zfish   878 LAVVIMKIATPSISEAKARDEKDVAKSMIKTIVFLSPVLGLSWVLGFFVLGLDLTVKPWAAL--V 940

  Fly   441 LYAHIVVNALQ-TPLLLYICVLRQRHVTFLLKK 472
            .|:..:.|:|| ..:||..||..::....|||:
Zfish   941 NYSFTIFNSLQGLFILLTNCVGEKKVRDALLKR 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tmB3_Methuselah-like	215..474	CDD:410632	66/293 (23%)
		TM helix 1	215..239	CDD:410632	7/15 (47%)
		TM helix 2	249..271	CDD:410632	5/25 (20%)
		TM helix 3	281..308	CDD:410632	10/39 (26%)
		TM helix 4	324..344	CDD:410632	2/19 (11%)
		TM helix 5	371..396	CDD:410632	7/24 (29%)
		TM helix 6	409..435	CDD:410632	6/38 (16%)
		TM helix 7	438..463	CDD:410632	8/25 (32%)
adgrf3a	XP_021322955.3	None