DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl5 and adgrf3a

DIOPT Version :9

Sequence 1:NP_001287291.1 Gene:mthl5 / 41438 FlyBaseID:FBgn0037960 Length:497 Species:Drosophila melanogaster
Sequence 2:XP_021322955.1 Gene:adgrf3a / 101886922 ZFINID:ZDB-GENE-131121-607 Length:949 Species:Danio rerio


Alignment Length:293 Identity:66/293 - (22%)
Similarity:114/293 - (38%) Gaps:72/293 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   224 GISLVILLVIAII-YFILPTLSRDLVGNI----VTTIAMCLMVSQAADLVRIFTELTSHVSFI-- 281
            |||::.||...|| ..:...:.:..:.|.    :..|::||:::....|.      ||....|  
Zfish   661 GISILSLLACLIIKVLVWDAVVKSPISNFRHVALFNISLCLLLAHCMFLT------TSKPESIPP 719

  Fly   282 ----VADIILCFSLLAAFFWLNSFGF-------YIWKTFRSRNVF--LRVTDGRKYCYYSAYAWG 333
                :..:|..|..||.|||:....|       |::...| :.||  |.:|.|          :.
Zfish   720 NWCSILTLIKHFFFLAVFFWMLCLSFVLLHQMIYVFDRLR-KKVFLGLSITVG----------YA 773

  Fly   334 CTATMAALAVFAHFFLDAESYKQEHMVGE--QETIGWL--------GICIFFAPIACTILVNIFF 388
            | ..:|....:..|...||        ||  .::..||        .|..|..||...:.||:|.
Zfish   774 C-PIIAVAVTYISFNNGAE--------GEYYSKSTCWLTYKGTLKGSIFAFIIPIGAIVFVNLFT 829

  Fly   389 YVTTRKLINRRTVYGRIAHKLK--ANFIMFSLMLL--VMSIAWL--FLIMS-------WLQMEGL 440
            .......|...::....|...|  |..::.:::.|  |:.::|:  |.::.       |..:  :
Zfish   830 LAVVIMKIATPSISEAKARDEKDVAKSMIKTIVFLSPVLGLSWVLGFFVLGLDLTVKPWAAL--V 892

  Fly   441 LYAHIVVNALQ-TPLLLYICVLRQRHVTFLLKK 472
            .|:..:.|:|| ..:||..||..::....|||:
Zfish   893 NYSFTIFNSLQGLFILLTNCVGEKKVRDALLKR 925

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl5NP_001287291.1 7tm_4 212..451 CDD:304433 57/269 (21%)
adgrf3aXP_021322955.1 GPS 604..641 CDD:307782
7tm_GPCRs 649..926 CDD:333717 66/293 (23%)
TM helix 1 652..676 CDD:320095 7/14 (50%)
TM helix 2 691..712 CDD:320095 4/26 (15%)
TM helix 3 723..745 CDD:320095 7/21 (33%)
TM helix 4 766..782 CDD:320095 5/26 (19%)
TM helix 5 805..831 CDD:320095 7/25 (28%)
TM helix 6 855..881 CDD:320095 4/25 (16%)
TM helix 7 890..915 CDD:320095 8/26 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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