DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl5 and adgrf11

DIOPT Version :9

Sequence 1:	NP_001287291.1	Gene:	mthl5 / 41438	FlyBaseID:	FBgn0037960	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_005160858.1	Gene:	adgrf11 / 100537132	ZFINID:	ZDB-GENE-121214-165	Length:	691	Species:	Danio rerio

Alignment Length:	345	Identity:	77/345 - (22%)
Similarity:	123/345 - (35%)	Gaps:	118/345 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 FLLRKILNPIFH---GISLVILLVIAIIYFILPTLSRDLVGNIV-TTIAMCLMVSQAADLVRIFT 272
            |:..|.|:.|.:   ||| |:.|||::|           :|.|| ||:..    |.:|.| |...
Zfish   368 FIDDKALDYITYTGLGIS-VLSLVISLI-----------IGAIVWTTVTK----SNSAYL-RHVC 415

  Fly   273 ELTSHVSFIVADIILCFSL----------------LAAFFWLNSF--GFYIWKTFRSRNVFLRVT 319
            .:.::||.:|||:  ||.:                .|..|.::.|  .|:.|....:..:....|
Zfish   416 LVNTNVSLLVADV--CFIIGASIVQPGQLAPVGPCTAVAFSMHLFFLAFFFWMLISAMLLLYMTT 478

  Fly   320 DGRKYCYYSAYAWGCTATMAALAVF----AHFFLDAESYKQEHMVGE---QETIGWL------GI 371
                    ..|:....|.|.|:|.|    |...:...:|......|:   :..:.||      .:
Zfish   479 --------MVYSQMSRAKMMAIAFFLGYGAPLLIVVITYGLTAREGKYILEADVCWLNFDETKAL 535

  Fly   372 CIFFAPIACTILVNIFFYVT-------TRKLINRRTVYGRIAHKLKANFI-MFSLMLLVMS---- 424
            .||.:..:....||:...:.       .||..|:.|           |.: ..:.::|::|
Zfish   536 QIFVSLASSFTAVNVLIIIVVLYKMLIVRKQQNKET-----------NILPTVTRVVLIVSPLFG 589

  Fly   425 IAW----------------LFLIMSWLQ-----MEGLLYAHIVVNALQTPLLLYICVLRQRHVTF 468
            :.|                :|.|::.||     :.|||....|.|||.....|       |:.|.
Zfish   590 VTWGLGIGTMLSPDYGIHLVFTILNSLQGIFNLVSGLLVNSQVRNALAERWSL-------RNFTS 647

  Fly   469 LLKKTCCYNE-----PPSAN 483
            ..:.....||     |||.|
Zfish   648 SNRTRTIQNEQVLFRPPSRN 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	67/306 (22%)
adgrf11	XP_005160858.1	GAIN	143..>227	CDD:293098
		GPS	318..363	CDD:280071
		7tm_4	374..620	CDD:304433	59/283 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810