Protein Alignment mthl5 and adgre15

DIOPT Version :10

• Sequence 1: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_021333205.2
• Gene: adgre15 / 100536619
• ZFINID: ZDB-GENE-121214-33
• Length: 857
• Species: Danio rerio
• Alignment Length: 272
• Identity: 53/272 - (19%)
• Similarity: 112/272 - (41%)
• Gaps: 44/272 - (16%)

  Fly   228 VILLVIAIIYFILPTLSRDLVG-----NIVTTIAMCLMVSQAADLVRIFTELTSHVSFIVADIIL 287
            ::.:::.:::|.|..||..|..     |.|..|.:|:.: .:|.|:.:.|:  ..:|.|....:|
Zfish   591 LVCVIVGLVFFSLALLSFALCQWSPGVNNVARINICISL-LSAHLLFLLTQ--QFLSLIRPQQVL 652

  Fly   288 CFSL--LAAFFWLNSFGFYIWKTFRSRNVFL------RVTDGRKYCYYSAYAWGCTATMAALAVF 344
            |.::  |..|.:|::|   :|....:..:|:      :::..::....|.:.......:|.:.|.
Zfish   653 CVAIAGLLHFLFLSAF---VWMFIEAVLLFICVKNLSQISSKKREVLSSGFLCVIGYVLAMVVVC 714

  Fly   345 AHFFLDAESYKQEH-MVGEQETIGWLGICIFFAPIACTILVN--IFFYVTTRKLINRRTVYGRIA 406
            ....|..|.|..|| .:...|...|    .|..|:...:.:|  :||.:........:.:...::
Zfish   715 VSIGLVPEGYGSEHCWIKTDEGFIW----SFLGPVCVILALNLILFFKIVITLNSTLKNLNAEVS 775

  Fly   407 HKLKANFIMFSLM--LLVMSIAWLFLIMSWLQ--MEGLLYAHIVVNALQ-TPLLLYICVL----R 462
            ...:...::|..:  .:|:...|   |:.:..  .|.|....::.|:.| |.:.|..|:|    |
Zfish   776 QMKQTKVMVFKTLGQFVVLGCPW---ILGFFTNGSEVLEIVFLIFNSQQGTFIFLIYCLLNNEIR 837

  Fly   463 QRHVTFLLKKTC 474
            |::      |.|
Zfish   838 QQY------KNC 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl5	NP_001287291.1	7tmB3_Methuselah-like	215..474	CDD:410632	52/270 (19%)
		TM helix 1	215..239	CDD:410632	0/10 (0%)
		TM helix 2	249..271	CDD:410632	6/26 (23%)
		TM helix 3	281..308	CDD:410632	8/28 (29%)
		TM helix 4	324..344	CDD:410632	2/19 (11%)
		TM helix 5	371..396	CDD:410632	5/26 (19%)
		TM helix 6	409..435	CDD:410632	4/27 (15%)
		TM helix 7	438..463	CDD:410632	8/29 (28%)
adgre15	XP_021333205.2	None