Protein Alignment CG31368 and HCS1

DIOPT Version :9

• Sequence 1: NP_996198.2
• Gene: CG31368 / 41437
• FlyBaseID: FBgn0051368
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_012908.1
• Gene: HCS1 / 853852
• SGDID: S000001500
• Length: 683
• Species: Saccharomyces cerevisiae
• Alignment Length: 652
• Identity: 155/652 - (23%)
• Similarity: 262/652 - (40%)
• Gaps: 189/652 - (28%)

  Fly   731 TFMDYNHLEASFPQYNLK-CEVPVENRQPPFRLIFEDVPIQKESDGEDP-EEKPEEKLTKSILVQ 793
            ||..|:.|      |.|| ..|...||.        :..::|.|:...| ::|         ::|
Yeast   141 TFYSYSKL------YILKTTNVVTYNRM--------ESTMRKLSEISSPIQDK---------IIQ 182

  Fly   794 PYKYEARGPYPSDKPKQNSIRF-----TPTQVEAIRAGMQPGLTLVVGPPGTGKTDVAVQIISNI 853
             |....|...|:....||...|     ..:|..||...:...||::.||||||||...:::|..:
Yeast   183 -YLVNERPFIPNTNSFQNIKSFLNPNLNDSQKTAINFAINNDLTIIHGPPGTGKTFTLIELIQQL 246

  Fly   854 YHNHPNQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEALETEKDYSRYGRVNYVLAKR 918
            ...:|.:|.||...||.:::.:.|::..| :....|||:||....|::.|.:|
Yeast   247 LIKNPEERILICGPSNISVDTILERLTPL-VPNNLLLRIGHPARLLDSNKRHS------------ 298

  Fly   919 MDLLSQVQKLQEALGVSGDNAYTCETAGYFYLYNVMARWEKFQSQISVHKGEADAEKLRAEFEKE 983
            :|:||:...:.:.:                             ||        :.:||..|.:|
Yeast   299 LDILSKKNTIVKDI-----------------------------SQ--------EIDKLIQENKK- 325

  Fly   984 FPFGKFFADAPQPLFKGANYDELMDIACSNFRYISDIFNELEEFRAFELLRTGLDRSKYLLVKEA 1048
                                       ..|::...:.:||:      :|||..|.:.::..:|:.
Yeast   326 ---------------------------LKNYKQRKENWNEI------KLLRKDLKKREFKTIKDL 357

  Fly  1049 KI---IAMTCTHAALKRKELVNL-----GFR-YDNILMEESAQILEIETFIPLLLQNPLDGLNRL 1104
            .|   |.:|..|.:..| ||.:|     .|: :|.::::|.:|.:|.:.:|||:...     |:.
Yeast   358 IIQSRIVVTTLHGSSSR-ELCSLYRDDPNFQLFDTLIIDEVSQAMEPQCWIPLIAHQ-----NQF 416

  Fly  1105 KRWIMIGDHHQLPPVIKNMAFQK-YSNMEQSLFTRLVRLGVPTVD----LDGQGRARASIC---- 1160
            .:.::.||:.||||.||....:. ..|:|.:||.|:::: .|..|    |:.|.|....|.
Yeast   417 HKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFDRIIKI-FPKRDMVKFLNVQYRMNQKIMEFPS 480

  Fly  1161 -SLYKWRY--------KKLEDLQHIFERDEYKQANPGFVHDYQLINVEDFKGVGESEPNPYFYQN 1216
             |:|..:.        :.|.||..:       .|.|....|...|.:..:...|:.     |.:.
Yeast   481 HSMYNGKLLADATVANRLLIDLPTV-------DATPSEDDDDTKIPLIWYDTQGDE-----FQET 533

  Fly  1217 LAEAEYIVAVY------------MYMRLLGYPAAKISILTTYNGQ----KHLIRDVINARCGNNP 1265
            ..||..:.:.|            ..:|....|...|.:::.||.|    |.||.|.:...
Yeast   534 ADEATILGSKYNEGEIAIVKEHIENLRSFNVPENSIGVISPYNAQVSHLKKLIHDELKLT----- 593

  Fly  1266 LIGWPHKITTVDKYQGQQNDYILISLVRTK---AVGHLRDVRRLVVAMSRARLGLYVFGRVSLFK 1327
                ..:|:|||.:||::.|.|::||||:.   .||.|::.|||.|||:|.|..|.|.|.:.:.:
Yeast   594 ----DIEISTVDGFQGREKDVIILSLVRSNEKFEVGFLKEERRLNVAMTRPRRQLVVVGNIEVLQ 654

  Fly  1328 NC 1329
            .|
Yeast   655 RC 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31368	NP_996198.2	Aquarius_N	33..815	CDD:293008	20/85 (24%)
		AAA_11	818..1123	CDD:289831	72/313 (23%)
		AAA_19	821..893	CDD:289986	24/71 (34%)
		DNA2	<1012..1348	CDD:224037	95/364 (26%)
		UvrD_C_2	1131..1321	CDD:304668	59/225 (26%)
HCS1	NP_012908.1	TIGR00376	15..679	CDD:273041	155/652 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1555
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2146
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.950