Protein Alignment CG31368 and Setx

DIOPT Version :10

• Sequence 1: NP_996198.2
• Gene: CG31368 / 41437
• FlyBaseID: FBgn0051368
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_001137907.1
• Gene: Setx / 38904
• FlyBaseID: FBgn0035842
• Length: 1676
• Species: Drosophila melanogaster
• Alignment Length: 963
• Identity: 197/963 - (20%)
• Similarity: 340/963 - (35%)
• Gaps: 285/963 - (29%)

  Fly   520 GGWARMAL--PIASFAVVEVAKPHLGEKKPSRVRADVGVTLSVRREI-----------------K 565
            ||:....:  |....|..:.|||  ..|||...:.....|.|.:.:.                 :
  Fly   813 GGFLTKGVDGPAPKLAKTDNAKP--PPKKPVPKQPPAIETFSQQLQAADKAVLHPQPQCSRPVER 875

  Fly   566 AEWENLRKHDVCFLITVKPTQPYGTKYKHREPFVPQVGLVSVRGCEVEGMLDANGRVIEDGPEPR 630
            .|.|..|....|..:|....:.|..|.:..:....::..|....       |.....||......
  Fly   876 KEAELARNQRTCNKVTFAEMELYHQKAEDSKKLQKKLRKVHFND-------DVKVHCIERVKGAS 933

  Fly   631 PQLQGENRCYRVWLDSNQYRLD--------MDD---------------LQEGADDVYESFNILMR 672
            .::||...|.::.|.|.:.|.:        ::|               |:.|:.|.....::||.
  Fly   934 SKVQGRKECIKLRLSSYRERREWIRRENKPVNDIRQHSRSILKWANQWLKHGSVDAVAEQDVLMP 998

  Fly   673 RKPKENNFKAVLETIRHLMNTECVVPPWLHDILLGYGDPGAAHYSNMPNQE---------RSLEF 728
            ..|:.::||...|....||..| ::.....|..:...:..:....|:..|:         .|..|
  Fly   999 IPPEFDSFKNYREIFVPLMKLE-LLSTIERDYKINNKNTFSVSLINVETQDMCYRLVTRVNSKPF 1062

  Fly   729 --------------NDTFMDYNHLEASFPQYNLKCEVPVENRQPPFRLIFEDVPIQKESDGEDPE 779
                          .:||.  |.||..|...|:            |.|.||   |.|:...|:..
  Fly  1063 GKFVLYTLYCCGMLKETFA--NLLELKFVSGNV------------FDLTFE---ILKQDISEEKL 1110

  Fly   780 E-------------------------------------KPEEKLTK-SILVQPYKYEARGPYPSD 806
            :                                     ||.:.:.: |:..||:.:  :|.:..:
  Fly  1111 KNIKQLTARPVVDSLRVELGALSAVHQLRSSPLCRRILKPTQTVNEVSLPKQPFTF--KGCHKLN 1173

  Fly   807 KPKQNSIRFTPTQVEAIRAGMQPGLTLVVGPPGTGKTDVAVQI-ISNIYHNHP---NQRTLIVTH 867
            :.::|.:..|   .:.|...:||.|||:.|||||||:.|..:: :..:|.|..   :::.||..|
  Fly  1174 EHQENIVLHT---YQRIIDDLQPSLTLIQGPPGTGKSRVISELCLQTLYGNAAKTLDRKILICAH 1235

  Fly   868 SNQALNQ----LFEKIMALDIDERHLLRLGHGEE--------ALET------EKDYSRYGRVNYV 914
            ||.|::.    |...:..::.|:.||||.|..|:        :||.      |:...|..:.|..
  Fly  1236 SNTAVDHIVGLLGSVLRVMNRDQFHLLRFGMHEKMSHYSRPFSLEAHFNKAKEQKLQRVSKENAE 1300

  Fly   915 LAKRM--DLLSQVQKLQEALGVSGDNAYTCETAGYFYLYNVMARWEKFQSQISVHKGEADAEKLR 977
            :.|:.  ||..::|:|:|...::..           ||...:.:.||....||
  Fly  1301 ILKKQHNDLKDEIQQLKEKTNLTST-----------YLLQQLQQKEKKLQLIS------------ 1342

  Fly   978 AEFEKEFPFGKFFADAPQPLFKGANYDELMDIACSNFRYISDIFNELEEFRAFELLRTGLDRSKY 1042
                                                 ..:|....:.|||..           .:
  Fly  1343 -------------------------------------NQLSPPLTQREEFEI-----------SH 1359

  Fly  1043 LLVKEAKIIAMTCTHAALKRKELVNLGFRYDNILMEESAQILEIETFIPLLLQNPLDGLNRLKRW 1107
            :.|..|.||..|.:...    :|.|....:|..:::|:.|..|..|.:|:..     ||..:
  Fly  1360 MCVTRANIICTTLSSCV----KLANYVDFFDICIVDEATQCTEPWTLLPMRF-----GLTHM--- 1412

  Fly  1108 IMIGDHHQLPPVIKN-------MAFQKYSNMEQSLFTRLVRLG------VPTVDLDGQGRARASI 1159
            :::||..|||.|:.:       ::...:..:::||.|:|.:.|      .....|..|.|....|
  Fly  1413 VLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEI 1477

  Fly  1160 CSLYKWRYKKLEDLQHIFERDEYKQANPGFVHDYQLINVE---DFKGVGESEPNPYFYQNLAEAE 1221
            |   :|..:...:.|.|......:.|:|  :..|.:||::   |..|.....     ..|..||.
  Fly  1478 C---RWPNQYFYEDQLINAECTARFASP--LIPYCVINLKYTCDSNGAQNKS-----ISNNEEAR 1532

  Fly  1222 YIVAVYMYMRLLGYPAAKIS--ILTTYNGQKHLIRDVINARCGNNPLIGWPHKITTVDKYQGQQN 1284
            ::..:...|. ...|:.:.|  :::.|..|.:.:..||.:.....|        .|||.|||.:.
  Fly  1533 FVAKLLTEMD-KHMPSKRFSYGLISPYQNQCYALSQVIPSHMNITP--------QTVDSYQGLEK 1588

  Fly  1285 DYILISLVRTKAVGHLRDVRRLVVAMSRARLGLYVFGR------VSLFKNCLE 1331
            |.|:||..||:..|.|.:.:||.||::|.|..|.:.|.      |.:::|.|:
  Fly  1589 DVIIISNARTRGCGFLTNYQRLNVALTRPRRCLVICGNFEDLKSVEMWRNLLD 1641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31368	NP_996198.2	Aquarius_N	33..815	CDD:435319	68/397 (17%)
		EEXXQc_AQR	810..1168	CDD:350693	85/394 (22%)
		SF1_C_Upf1	1156..1339	CDD:350195	48/187 (26%)
Setx	NP_001137907.1	FHA	12..94	CDD:438714
		AAA_11	1175..1428	CDD:404072	74/338 (22%)
		DNA2	<1299..1646	CDD:440729	93/445 (21%)