Protein Alignment CG31368 and Upf1

DIOPT Version :10

• Sequence 1: NP_996198.2
• Gene: CG31368 / 41437
• FlyBaseID: FBgn0051368
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Alignment Length: 913
• Identity: 194/913 - (21%)
• Similarity: 336/913 - (36%)
• Gaps: 310/913 - (33%)

  Fly   598 FVPQ-----VGLVSVRGCEVEGML-DANGRVIEDGPEPRPQLQGENRCYRVWL-----DSNQYR- 650
            |:|.     |.|:..:.|..:..| |.|.    |..:.:|.:  .:||:..||     :..|.|
  Fly   173 FIPAKADSVVVLLCRQPCAAQNSLKDMNW----DQEQWKPLI--ADRCFLAWLVKQPSEQGQLRA 231

  Fly   651 --------------------LDMDDLQE-GAD-----------DVYE---SFNILMR------RK 674
                                ....||:: |.|           |.|:   :|..|:|      :|
  Fly   232 RQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEAEYDQK 296

  Fly   675 PKENNFKAVLE----------TIRH--LMNTECVVPPWLHDILLGYGDPGAAHYSNMPNQERSLE 727
            .||:..:..:|          ||.:  |..|:       .|:.|.:||....||..        |
  Fly   297 LKESATQENIEVRWDVGLNKKTIAYFTLAKTD-------SDMKLMHGDELRLHYVG--------E 346

  Fly   728 FNDTFMDYNHLEASFPQYNLKCEVPVENRQPPFRLIFEDVPIQKESDGEDPEEKPE--------- 783
            ..:.:.:..|:          .:|| :|       ..:||.::.:|....|.:...
  Fly   347 LYNPWSEIGHV----------IKVP-DN-------FGDDVGLELKSSTNAPVKCTSNFTVDFIWK 393

  Fly   784 ----EKLTKSIL--------VQPYKYEA---------------RGPYPSDKPKQNSIRFTP---- 817
                :::|:::.        |..:.|..               |||    :||..|....|
  Fly   394 CTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGP----QPKLFSAPHLPDLNR 454

  Fly   818 TQVEAIRAGMQPGLTLVVGPPGTGKTDVAVQIISNIYHNHPNQRTLIVTHSNQALNQLFEKIMAL 882
            :||.|::..:|..|:|:.||||||||..:..|:..:...| ....|:...||.|::||.|||...
  Fly   455 SQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLH-GGTVLVCAPSNTAVDQLTEKIHRT 518

  Fly   883 DIDERHLLRL-GHGEEALETEKDY-SRYGRVNYVLAKRMDLLSQVQKLQEALGVSGDNAYTCETA 945
            ::   .::|: ....||:::...: :.:.::     :.|:..|:::|||:....:|:
  Fly   519 NL---KVVRVCAKSREAIDSPVSFLALHNQI-----RNMETNSELKKLQQLKDETGE-------- 567

  Fly   946 GYFYLYNVMARWEKFQSQISVHKGEADAEKLRAEFEKEFPFGKFFADAPQPLFKGANYDELMDIA 1010
                                  ...||.::.|
  Fly   568 ----------------------LSSADEKRYR--------------------------------- 577

  Fly  1011 CSNFRYISDIFNELEEFRAFELLRTGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNI 1075
              |.:            ||.|          ..|::.|.:|..||..|...|...|    ::.:|
  Fly   578 --NLK------------RAAE----------NQLLEAADVICCTCVGAGDGRLSRV----KFTSI 614

  Fly  1076 LMEESAQILEIETFIPLLLQNPLDGLNRLKRWIMIGDHHQLPPVI--KNMAFQKYSNMEQSLFTR 1138
            |::||.|..|.|..:|::|        ..|:.|::|||.||.||:  |..|   .:.:.||||.|
  Fly   615 LIDESMQSTEPECMVPVVL--------GAKQLILVGDHCQLGPVVMCKKAA---RAGLSQSLFER 668

  Fly  1139 LVRLGVPTVDLDGQ-----------------GRARASICSLYKWRYKKLEDLQHIFERDEYKQAN 1186
            ||.||:....|:.|                 |..:..:|:  :.|..||:......||..:....
  Fly   669 LVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCA--EDRRLKLDFPWPQPERPMFFLVT 731

  Fly  1187 PGFVHDYQLINVEDFKGVGESEPNPYFYQNLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKH 1251
            .|         .|:..|.|.|      :.|..||..:..:.......|....:|.|:|.|.||:.
  Fly   732 QG---------QEEIAGSGTS------FLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRA 781

  Fly  1252 LIRDVINARCGNNPLIGWPHKITTVDKYQGQQNDYILISLVRT---KAVGHLRDVRRLVVAMSRA 1313
            .:...:..:...:..:....:|.:||.:||::.|.|::|.||:   :.:|.|.|.|||.||::||
  Fly   782 YLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRA 846

  Fly  1314 RLGLYVFG------RVSLFKNCLELQQTFKLLTQ---RPLKLSLVPEDKFPTDRLASAAVASQDI 1369
            :.|:.:.|      :..|:.:.|...:..|:|.:   ..||.||:...| |...:.|..:.:..:
  Fly   847 KFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLNNLKESLIHFQK-PKKLVNSMNIGAHFM 910

  Fly  1370 KTV 1372
            .|:
  Fly   911 STI 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31368	NP_996198.2	Aquarius_N	33..815	CDD:435319	57/317 (18%)
		EEXXQc_AQR	810..1168	CDD:350693	85/382 (22%)
		SF1_C_Upf1	1156..1339	CDD:350195	46/191 (24%)
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391	16/81 (20%)
		1B_UPF1-like	302..390	CDD:394815	20/120 (17%)
		TIGR00376	355..880	CDD:273041	146/674 (22%)
		DEXXQc_UPF1	451..684	CDD:350797	80/343 (23%)