Protein Alignment CG6962 and smpd4

DIOPT Version :10

• Sequence 1: NP_650124.1
• Gene: CG6962 / 41436
• FlyBaseID: FBgn0037958
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: XP_031762695.1
• Gene: smpd4 / 100127861
• XenbaseID: XB-GENE-962467
• Length: 824
• Species: Xenopus tropicalis
• Alignment Length: 857
• Identity: 216/857 - (25%)
• Similarity: 355/857 - (41%)
• Gaps: 153/857 - (17%)

  Fly    10 LSSRLLTVLSLPLFERVHELSILFDRCSLRQVQEIFPHVVHSIFG-IDGNPLGWGLRTTTLENNP 73
            |.|.....::.|..:|..:|..:.:....:::..|||.::.::|| :||:.|||.||......||
 Frog    14 LGSLKADCVTKPFLQRCQDLVRVIEDFPAKELHAIFPWLIETVFGSLDGSILGWNLRGLHERINP 78

  Fly    74 VQFQTLHQFFGVCGPLMHVCHRLLVDQYKFELDINLLPAKFVSLLQNGQNPS--FYAELINVETM 136
            ::|.|..:|....|.:|.:.::|..::||::..::.||:...:.:|....|.  .|...|.....
 Frog    79 LEFHTALEFLDPSGAMMKLVYKLQAEEYKYDFPVSFLPSPVRASIQERVLPECPLYHNKIQFPAS 143

  Fly   137 MHQVSTLSLNAFDFYVIHFVLYALQPL-----HSINPIAMQIHNVRSKTVYLKLVAEYLNNFLPL 196
            ......|:||:|::::.||....|:..     |..:         .:.:.|..||.:||..|||
 Frog   144 GGISFNLALNSFEYFMFHFAFCLLKQRSFPQGHYFS---------TADSAYYILVDKYLKWFLP- 198

  Fly   197 LPDARIEPVHFSSGVKAPQPLPAQALQPQRQPRYIKIP-SSYRNGGNVSGGGGIPSASVGVGNIS 260
             .:..:.|.| |.......||||        ||...|. :||         |..|  |:...:||
 Frog   199 -AEGNVPPPH-SPNTGGTVPLPA--------PRSPSISFASY---------GSHP--SLLKRHIS 242

  Fly   261 PQ---SNSPSASSNRAYAWRSESVLHFFVDIWL-----------------------RYDIESEHH 299
            .|   :..|:|..    .||:|::|..||:|||                       |..:.|..|
 Frog   243 HQHLVNADPAAQE----IWRTETLLQVFVEIWLHHYSLEMYQKMQSPNAKLEALHNRLSVSSATH 303

  Fly   300 L----------------PSSDFVRGVRTLVKQVHFFANG--------AQHDH--SSLCALRKVSL 338
            :                |:.:.|..||.|||.:|.|:|.        :.|.|  |.|..|::|.:
 Frog   304 VYPALPGSLHSYQELFQPTEEHVLVVRLLVKHLHTFSNSLRPEQVSPSTHSHTASPLEELKRVVV 368

  Fly   339 -SMVKARIYAFIVGLIDRWPLDSSLMVVLELWLSYIQPWRYTIASLNNKTPSLSYRPPISSCFDG 402
             ..::.::|.|:......||||:|...|||:||||:|||||.:...:..:..:..| .:...:..
 Frog   369 PRFIQQKLYIFLQHCFGHWPLDASFRAVLEMWLSYVQPWRYVLERSSPVSGEMQNR-NVPEKWST 432

  Fly   403 FIIDNLIMYTHIFMQLLPHFGRLDYTVYRNAFMLYRLATIFSQHDLVDKLQRFEAI-----HAGN 462
            |:.:||:.||.:|::.|....|.|....:||.|::|.|.:|||.:|.:.:|..|.:     |.
 Frog   433 FVQENLLFYTKLFLRFLNRALRSDLVNPKNALMVFRAAKVFSQQNLPEMIQNGEQLFLKPEHV-- 495

  Fly   463 SFGFDSPQRQVNIM---NKSVSPGTPWNQAVNISSAKLFSYTMQTQ------METFLLLISMARN 518
                 .|.||..::   |...|..:.|...:..:|.|:.|:....:      |:.|   .:.|||
 Frog   496 -----IPHRQHRLLLTPNLGGSFLSSWQPPITDTSLKVKSHVFSLEGQDCHYMQMF---GTEARN 552

  Fly   519 SVLR---------DIAK-LRNEIAERQRSEGFLKNF------YKKIFGECTQEEVTLREFSRIPE 567
            .|||         ..|| :.|...:...::.||..|      :...:.....:|.......:..|
 Frog   553 LVLRLAQMISQAKQTAKSISNHSPDSSANQSFLSWFGLGSPDFNGSYNGGDLDEAGYDTIRKTDE 617

  Fly   568 VLRQCIDAFCRTFNVDQANLSM----HETLPEEPSVPSAPAVQNFSFFDASDTLDTSKLNPHQM- 627
            .|.:.:|..|:.|.::...|..    .::..:|......|     ....:.|.|..:.|..:|:
 Frog   618 HLEKALDYICQIFRLNPTQLGQLTANCDSSQDENGKNKLP-----DCIQSEDGLVLTSLGRYQII 677

  Fly   628 -SLNASSLHAAVDPATLPIQTNEVRALVRMLHFVSEKINNKYGSQLQGFYVRDDYFGKVARQLLY 691
             .|....:....||...||::.|...|||.|..:|..:|.::...:.....|:|:.|||.|..|.
 Frog   678 NGLRKFEVEYRGDPELQPIRSYENAMLVRYLFRLSSVLNERFAESMGTLCAREDFLGKVCRCHLT 742

  Fly   692 APMTEQWFDKSSGHVEIC-ENLVPPRVCLRPLGSIPALTTIGCSMIFGQLVWGAPLLGIFILATV 755
            :...:   .|.|....|| .....||:.||.|.|...||.:....|.|.|:...||...|:|...
 Frog   743 SCSRK---GKKSPITSICPSEPTTPRIRLRFLASYRTLTLLFMFYILGPLLSLGPLSCTFLLLIG 804

  Fly   756 LLVYIMLQALFS 767
            .:.|..:|.|.|
 Frog   805 CMFYATVQTLLS 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6962	NP_650124.1	mit_SMPDase	21..759	CDD:464282	210/836 (25%)
smpd4	XP_031762695.1	mit_SMPDase	9..813	CDD:464282	213/852 (25%)