Protein Alignment CG6959 and slit3

DIOPT Version :10

• Sequence 1: NP_650122.1
• Gene: CG6959 / 41434
• FlyBaseID: FBgn0037956
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001072738.1
• Gene: slit3 / 780195
• XenbaseID: XB-GENE-991050
• Length: 1519
• Species: Xenopus tropicalis
• Alignment Length: 438
• Identity: 91/438 - (20%)
• Similarity: 148/438 - (33%)
• Gaps: 186/438 - (42%)

  Fly    23 NSSSCGPNFPAACSCGQEMYESEMQYVVNCTNAGLVNTSVLEFMPEQVEVLIFTGNRITELPWNV 87
            |:.||    |:||:|...        ||:|...||  |.:...:||.:..:....|.|..:|..|
 Frog   272 NAVSC----PSACTCSNN--------VVDCRGKGL--TEIPANLPEGIIEIRLEQNSIKAIPAGV 322

  Fly    88 FGSINNYKQLRIVDMSSNHIREIR----------------GKSYHHVPR--------VERLILNH 128
            |   ..||:|:.:|:|.|.|.||.                |.....:|:        ::.|:||.
 Frog   323 F---TPYKKLKRIDISKNQISEIAADAFSGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNA 384

  Fly   129 NNLS---------------ISRYEDEVNHHHPRVFSNFINLQSLH--------------LTDAFE 164
            |.::               :|.|::::......:|:...::|:||              |.|..:
 Frog   385 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQ 449

  Fly   165 DN---------SSPQL------------------SEDLH-----DIFV----------------- 180
            ||         :||:.                  |||..     |.|:
 Frog   450 DNPIETSGARCTSPRRLANKRISQIKSKKFRCTGSEDYRSKFSGDCFMDLVCPEKCRCEGTIVDC 514

  Fly   181 -NSQLVKL--------QKLHLEQNEITHFKDRNVFCDLPSLRDLHLGDNDLRDLN---FE----- 228
             |.::.::        ..|.|..||||..:...:|..||:||.::|.:|.::|:.   |:
 Frog   515 SNQKISRIPSYLPEYTSDLRLNDNEITVLEATGIFKKLPNLRKINLSNNKIKDIREGAFDGAAGV 579

  Fly   229 ---------------------------------VRCLNN--------LRFLDLERNKFSFVKPTD 252
                                             :.|:||        :|.|.|..|:.:.:.|..
 Frog   580 QELMLTGNQLESVHGRMFRGLVGLKTLMLRSNLMSCINNDTFTGLSSVRLLSLYDNRITTITPGA 644

  Fly   253 LRVLNELEERPNRTANLIVDFNLNPFGCDCRTAPFRAWITTTRVTVRN 300
            ...|..|.     |.||:    .|||.|:|..|....|:...||...|
 Frog   645 FNTLVSLS-----TINLL----SNPFNCNCHLAWLGKWLRKKRVVSGN 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6959	NP_650122.1	LRR	<69..>278	CDD:443914	67/368 (18%)
		leucine-rich repeat	70..96	CDD:275380	6/25 (24%)
		leucine-rich repeat	97..120	CDD:275380	8/38 (21%)
		leucine-rich repeat	121..153	CDD:275380	7/46 (15%)
		leucine-rich repeat	154..186	CDD:275380	15/95 (16%)
		leucine-rich repeat	187..211	CDD:275380	8/31 (26%)
		leucine-rich repeat	212..234	CDD:275380	7/62 (11%)
		leucine-rich repeat	235..258	CDD:275380	6/22 (27%)
		LRRCT	276..328	CDD:214507	10/25 (40%)
slit3	NP_001072738.1	LRRNT	29..60	CDD:214470
		LRR	<58..>213	CDD:443914
		leucine-rich repeat	60..82	CDD:275380
		leucine-rich repeat	83..106	CDD:275380
		leucine-rich repeat	107..130	CDD:275380
		leucine-rich repeat	131..154	CDD:275380
		leucine-rich repeat	155..178	CDD:275380
		leucine-rich repeat	179..202	CDD:275380
		leucine-rich repeat	203..305	CDD:275380	15/46 (33%)
		LRRCT	211..260	CDD:214507
		LRRNT	276..307	CDD:214470	13/44 (30%)
		leucine-rich repeat	307..328	CDD:275380	6/23 (26%)
		LRR	<327..662	CDD:443914	62/343 (18%)
		leucine-rich repeat	329..352	CDD:275380	7/22 (32%)
		leucine-rich repeat	353..373	CDD:275380	2/19 (11%)
		leucine-rich repeat	377..400	CDD:275380	4/22 (18%)
		leucine-rich repeat	401..422	CDD:275380	3/20 (15%)
		leucine-rich repeat	425..516	CDD:275380	14/90 (16%)
		leucine-rich repeat	533..554	CDD:275380	8/20 (40%)
		leucine-rich repeat	555..578	CDD:275380	6/22 (27%)
		leucine-rich repeat	579..602	CDD:275380	0/22 (0%)
		leucine-rich repeat	603..626	CDD:275380	3/22 (14%)
		leucine-rich repeat	627..650	CDD:275380	6/22 (27%)
		PCC	632..>719	CDD:188093	18/61 (30%)
		leucine-rich repeat	651..741	CDD:275380	14/42 (33%)
		LRR	<723..>855	CDD:443914
		leucine-rich repeat	742..772	CDD:275380
		leucine-rich repeat	773..796	CDD:275380
		leucine-rich repeat	797..820	CDD:275380
		leucine-rich repeat	821..842	CDD:275380
		PCC	826..>901	CDD:188093
		EGF	916..947	CDD:394967
		EGF_CA	952..989	CDD:238011
		EGF_CA	994..1027	CDD:238011
		EGF_CA	1031..1068	CDD:238011
		EGF_CA	1070..1106	CDD:238011
		LamG	1155..1308	CDD:238058
		GHB_like	1454..1517	CDD:473907