DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6959 and Tlr5

DIOPT Version :9

Sequence 1:NP_001138037.1 Gene:CG6959 / 41434 FlyBaseID:FBgn0037956 Length:425 Species:Drosophila melanogaster
Sequence 2:XP_017177186.1 Gene:Tlr5 / 53791 MGIID:1858171 Length:873 Species:Mus musculus


Alignment Length:426 Identity:90/426 - (21%)
Similarity:171/426 - (40%) Gaps:108/426 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 TNAGLVNTSVLEF----------------MPEQVEVLIFTGNRITELPWNVFGSINNYKQLRIVD 101
            |.|.|..:|||:.                ..:.:::|....|:|.::..|.|..:::   |::::
Mouse   296 TFASLARSSVLQLDLSHGFIFSLNPRLFGTLKDLKMLNLAFNKINKIGENAFYGLDS---LQVLN 357

  Fly   102 MSSNHIREIRGKSYHHVPRVERLILNHNNLSISRYED----------EVNHHHPRVF-------- 148
            :|.|.:.|:...:::.:|||..:.|..|::.|.:.:.          ::..:..:..        
Mouse   358 LSYNLLGELYNSNFYGLPRVAYVDLQRNHIGIIQDQTFRLLKTLQTLDLRDNALKAIGFIPSIQM 422

  Fly   149 -----SNFINLQSLHLTDAFEDNSSPQLSEDLHDIFVNSQLVKLQKLHLEQNEITHFKDRNVFCD 208
                 :..::|..:|.|..|.:.|..:| |:|.|::...::.:||.|.|.||.::..|..:...:
Mouse   423 VLLGGNKLVHLPHIHFTANFLELSENRL-ENLSDLYFLLRVPQLQFLILNQNRLSSCKAAHTPSE 486

  Fly   209 LPSLRDLHLGDNDLR-----DLNFEV-RCLNNLRFLDLERNKFSFVKP---TDLRVLNELEERPN 264
            .|||..|.|.:|.|:     .|.::| :.|:.|:.|.|..|..:|:.|   .||..|..|....|
Mouse   487 NPSLEQLFLTENMLQLAWETGLCWDVFQGLSRLQILYLSNNYLNFLPPGIFNDLVALRMLSLSAN 551

  Fly   265 R---------TANL----------------------IVDFNLNPFGCDCRTAPFRAWITTTRVTV 298
            :         .|||                      ::|...|.|.|:|..:.|.:|:..|.||:
Mouse   552 KLTVLSPGSLPANLEILDISRNQLFSPDPALFSSLRVLDITHNEFVCNCELSTFISWLNQTNVTL 616

  Fly   299 RNKDS-LMCFHSTGHVDAEPAHLLQMDMGQCADAIAAAATILNTAEDEPHYGDPEASHLQPQAHI 362
            ....: :.|.:        |..||             ..::.|.:.::  ..:.||......:..
Mouse   617 FGSPADVYCMY--------PNSLL-------------GGSLYNISTED--CDEEEAMRSLKFSLF 658

  Fly   363 SGHTATL-IFLLIVLTMILLGLLVALVYVSRDKLKY 397
            ...|.|| :||:|.|.:|....:..|.|.:..||.:
Mouse   659 ILCTVTLTLFLVITLVVIKFRGICFLCYKTIQKLVF 694

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6959NP_001138037.1 leucine-rich repeat 70..96 CDD:275380 5/25 (20%)
LRR_8 95..161 CDD:290566 12/88 (14%)
leucine-rich repeat 97..120 CDD:275380 4/22 (18%)
LRR_RI <116..>224 CDD:238064 29/135 (21%)
leucine-rich repeat 121..153 CDD:275380 4/54 (7%)
leucine-rich repeat 154..186 CDD:275380 9/31 (29%)
LRR_8 186..245 CDD:290566 21/64 (33%)
leucine-rich repeat 187..211 CDD:275380 7/23 (30%)
leucine-rich repeat 212..234 CDD:275380 8/27 (30%)
leucine-rich repeat 235..258 CDD:275380 9/25 (36%)
TPKR_C2 276..328 CDD:301599 13/52 (25%)
Tlr5XP_017177186.1 leucine-rich repeat 63..93 CDD:275380
LRR_8 <101..146 CDD:338972
leucine-rich repeat 112..135 CDD:275380
leucine-rich repeat 136..161 CDD:275380
leucine-rich repeat 162..186 CDD:275380
leucine-rich repeat 187..242 CDD:275380
leucine-rich repeat 243..304 CDD:275380 3/7 (43%)
leucine-rich repeat 305..328 CDD:275380 2/22 (9%)
LRR_8 308..363 CDD:338972 8/57 (14%)
leucine-rich repeat 329..352 CDD:275380 5/22 (23%)
LRR_8 352..411 CDD:338972 10/61 (16%)
leucine-rich repeat 353..376 CDD:275380 4/22 (18%)
leucine-rich repeat 377..400 CDD:275380 4/22 (18%)
PRK15370 <397..>597 CDD:185268 42/200 (21%)
leucine-rich repeat 401..429 CDD:275380 0/27 (0%)
leucine-rich repeat 430..464 CDD:275380 9/34 (26%)
leucine-rich repeat 465..489 CDD:275380 7/23 (30%)
leucine-rich repeat 490..518 CDD:275380 8/27 (30%)
leucine-rich repeat 519..542 CDD:275380 8/22 (36%)
leucine-rich repeat 543..561 CDD:275380 3/17 (18%)
leucine-rich repeat 565..585 CDD:275380 1/19 (5%)
PCC 569..>647 CDD:188093 15/100 (15%)
TIR 708..858 CDD:366714
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.