DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6959 and Toll-7

DIOPT Version :9

Sequence 1:NP_001138037.1 Gene:CG6959 / 41434 FlyBaseID:FBgn0037956 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_523797.1 Gene:Toll-7 / 37272 FlyBaseID:FBgn0034476 Length:1446 Species:Drosophila melanogaster


Alignment Length:427 Identity:85/427 - (19%)
Similarity:139/427 - (32%) Gaps:193/427 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 YVVNCTNAGLVNTSVLEFMPEQ--------------VEVLIFTGNRITELPWNVFGSINNYKQLR 98
            :|.|.|.|||:...||......              :::|....|.|..:..|.|..:.|   |.
  Fly   360 HVDNTTFAGLIRLIVLNLAHNALTRIDYRTFKELYFLQILNLRNNSIGHIEDNAFLPLYN---LH 421

  Fly    99 IVDMSSNHIREIRGKSYHHVPRVERLILNHNNLSISRYEDEVNHHHPRVFSNFINLQSLHLTDAF 163
            .::::.|.:..:..|.::.:..:.:|.||:|.:|:.         .|.||.|..:|:.|      
  Fly   422 TLNLAENRLHTLDDKLFNGLYVLSKLTLNNNLISVV---------EPAVFKNCSDLKEL------ 471

  Fly   164 EDNSSPQLSE---DLHDIFVNSQLVKLQKLHLEQNEITHFKDRN--------------------- 204
             |.||.||:|   .|.|      |..|:.|.|.:|:|..|.:::                     
  Fly   472 -DLSSNQLNEVPRALQD------LAMLRTLDLGENQIRTFDNQSFKNLHQLTGLRLIDNQIGNIT 529

  Fly   205 --VFCDLPSLRDLHLGDNDLR-------DLNFEVRCLN-----------------NLRFLDLERN 243
              :|.|||.|..|:|..|.::       |.|||:..:.                 :|.:|:|..|
  Fly   530 VGMFQDLPRLSVLNLAKNRIQSIERGSFDKNFELEAIRLDRNFLADINGVFATLVSLLWLNLSEN 594

  Fly   244 -----KFSFVKPTDLRVLN-------------ELEER---------------------PNRTANL 269
                 .::|: |::|:.|:             :|:|.                     ||....|
  Fly   595 HLVWFDYAFI-PSNLKWLDIHGNYIEALGNYYKLQEEIRVKTLDASHNRITEIGPMSIPNTIELL 658

  Fly   270 IVDFNL---------------------------------------------------NPFGCDCR 283
            .::.||                                                   |||.|||.
  Fly   659 FINNNLIGNVQPNAFVDKANLARVDLYANQLSKLQLQQLRVAPVVAPKPLPEFYLGGNPFECDCT 723

  Fly   284 TAPFRAWI-----TTTRVTVRNKD--SLMCF--HSTG 311
                ..|:     .|||...|..|  ::.|.  |:.|
  Fly   724 ----MDWLQRINNLTTRQHPRVMDMANIECVMPHARG 756

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6959NP_001138037.1 leucine-rich repeat 70..96 CDD:275380 6/25 (24%)
LRR_8 95..161 CDD:290566 14/65 (22%)
leucine-rich repeat 97..120 CDD:275380 3/22 (14%)
LRR_RI <116..>224 CDD:238064 34/140 (24%)
leucine-rich repeat 121..153 CDD:275380 9/31 (29%)
leucine-rich repeat 154..186 CDD:275380 11/34 (32%)
LRR_8 186..245 CDD:290566 22/110 (20%)
leucine-rich repeat 187..211 CDD:275380 9/46 (20%)
leucine-rich repeat 212..234 CDD:275380 8/45 (18%)
leucine-rich repeat 235..258 CDD:275380 8/40 (20%)
TPKR_C2 276..328 CDD:301599 15/45 (33%)
Toll-7NP_523797.1 LRR_8 135..201 CDD:290566
leucine-rich repeat 136..159 CDD:275380
leucine-rich repeat 160..190 CDD:275380
LRR_8 189..259 CDD:290566
leucine-rich repeat 191..214 CDD:275380
leucine-rich repeat 215..248 CDD:275380
LRR_RI 247..501 CDD:238064 41/165 (25%)
LRR_8 247..308 CDD:290566
leucine-rich repeat 249..273 CDD:275380
leucine-rich repeat 274..297 CDD:275380
LRR_8 297..356 CDD:290566
leucine-rich repeat 298..321 CDD:275380
leucine-rich repeat 322..345 CDD:275380
LRR_8 345..406 CDD:290566 10/45 (22%)
leucine-rich repeat 346..371 CDD:275380 6/10 (60%)
leucine-rich repeat 372..395 CDD:275380 2/22 (9%)
leucine-rich repeat 396..419 CDD:275380 5/22 (23%)
LRR_8 419..478 CDD:290566 18/77 (23%)
leucine-rich repeat 420..443 CDD:275380 3/22 (14%)
leucine-rich repeat 444..467 CDD:275380 9/31 (29%)
LRR_RI 466..622 CDD:238064 37/169 (22%)
leucine-rich repeat 468..488 CDD:275380 10/32 (31%)
LRR_8 491..549 CDD:290566 14/57 (25%)
leucine-rich repeat 491..514 CDD:275380 6/22 (27%)
leucine-rich repeat 515..536 CDD:275380 1/20 (5%)
leucine-rich repeat 539..562 CDD:275380 6/22 (27%)
leucine-rich repeat 563..585 CDD:275380 0/21 (0%)
leucine-rich repeat 586..626 CDD:275380 8/40 (20%)
leucine-rich repeat 627..653 CDD:275380 2/25 (8%)
LRRCT 716..772 CDD:214507 15/45 (33%)
LRRNT 796..830 CDD:214470
leucine-rich repeat 812..829 CDD:275380
leucine-rich repeat 833..854 CDD:275380
LRR_8 853..913 CDD:290566
leucine-rich repeat 855..878 CDD:275380
LRR_4 878..918 CDD:289563
leucine-rich repeat 879..902 CDD:275380
leucine-rich repeat 903..926 CDD:275380
leucine-rich repeat 927..953 CDD:275380
TIR 1098..1235 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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