DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6959 and iglr-3

DIOPT Version :10

Sequence 1:NP_650122.1 Gene:CG6959 / 41434 FlyBaseID:FBgn0037956 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_001293349.1 Gene:iglr-3 / 171771 WormBaseID:WBGene00021353 Length:488 Species:Caenorhabditis elegans


Alignment Length:350 Identity:84/350 - (24%)
Similarity:130/350 - (37%) Gaps:98/350 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 VPRVERLILNHNNL-SISRYEDEVNHHHPRVFSNFINLQSLHLT---------DA---FEDNSSP 169
            :|.|..|.|::|:: .|:.:..|           :..||||.|.         ||   ||.....
 Worm    48 LPNVLSLSLSNNSIFRITTFPSE-----------YRRLQSLRLDQCQLEKLDFDALSVFEQLREL 101

  Fly   170 QLSED-LHDIFVNSQLVKLQKLHLEQNEITHFKDRNVFCDLPSLRDLHLGDNDLRDLNFEVRCLN 233
            .:|.: |..:.:...|..|:.|:|..|..|:..|.:   .|.|||.:.|..|.|  ::...|.|.
 Worm   102 DVSRNSLSKLIIPRNLASLRVLNLAFNAFTYVPDMS---HLESLRLVDLSHNRL--ISVRPRMLP 161

  Fly   234 -NLRFLDLERNKFSFVKPTDLRVLNELEERPNRTANLIVDFNLNPFGCDCRTAPFRAWITTTRVT 297
             ||..:.|..|:|..:.|...  |::|:|         :|...|...|||....|..|       
 Worm   162 FNLEVVRLAANRFQHLSPWPF--LHKLQE---------LDVTFNDLECDCSLWHFVTW------- 208

  Fly   298 VRNKDSLMCFHSTGHVDAEPAHLLQMDM-GQ--CA----------------DAIAAAATILNTAE 343
               .:.|..|.||......|:.|.:..: |:  |.                ||.....|.|.|..
 Worm   209 ---AEKLALFDSTMLPCRRPSELRKSPIDGKTVCGPTVVTSSPESAVVSLDDAHVMCCTALATPS 270

  Fly   344 DEPHY---GDPEASHLQPQAHISGHTATLIFLLIVLTMIL--------LGLLVAL-----VYVSR 392
            .:.::   |...:|.|. |.|:| .:..|.|.|.:..:.|        :..|..|     .:|.|
 Worm   271 PQLYWQFNGKNISSGLS-QKHLS-ESGKLEFCLEIPKVRLKDMGKYKCVASLAGLNSSKEFHVER 333

  Fly   393 DKLKYMITPVFDNVAKKV----QYT 413
            ||:     |:..|.|:.:    |:|
 Worm   334 DKI-----PIVLNSAEGIMIYCQFT 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6959NP_650122.1 LRR <69..>278 CDD:443914 45/174 (26%)
leucine-rich repeat 70..96 CDD:275380
leucine-rich repeat 97..120 CDD:275380 0/1 (0%)
leucine-rich repeat 121..153 CDD:275380 6/32 (19%)
leucine-rich repeat 154..186 CDD:275380 12/44 (27%)
leucine-rich repeat 187..211 CDD:275380 7/23 (30%)
leucine-rich repeat 212..234 CDD:275380 7/22 (32%)
leucine-rich repeat 235..258 CDD:275380 6/22 (27%)
LRRCT 276..328 CDD:214507 13/54 (24%)
iglr-3NP_001293349.1 LRR <48..>197 CDD:443914 45/175 (26%)
leucine-rich repeat 51..73 CDD:275380 6/32 (19%)
leucine-rich repeat 74..97 CDD:275380 8/22 (36%)
leucine-rich repeat 98..119 CDD:275380 3/20 (15%)
leucine-rich repeat 120..141 CDD:275380 7/23 (30%)
leucine-rich repeat 142..163 CDD:275380 7/22 (32%)
leucine-rich repeat 164..185 CDD:275380 6/22 (27%)
Ig_3 243..319 CDD:464046 15/77 (19%)
Blue background indicates that the domain is not in the aligned region.

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