DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kyat and KYAT1

DIOPT Version :10

Sequence 1:NP_650121.1 Gene:Kyat / 41433 FlyBaseID:FBgn0037955 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_001274319.1 Gene:KYAT1 / 883 HGNCID:1564 Length:516 Species:Homo sapiens


Alignment Length:453 Identity:203/453 - (44%)
Similarity:289/453 - (63%) Gaps:14/453 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 CQLTLSAAKRSLREQFQLQALRHQQTAIKMEKFDLPKRLQGSTPSVWNEYIALAMQYKPLNLGQG 69
            |:  :.||:..||.......::.....:.|.|....:||.|...:.|.|::.||.::..:|||||
Human    68 CE--VPAAEGILRTGGAKLPIQGHPAKLAMAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQG 130

  Fly    70 FPDDAAPEYVTHSLADIAKEQNPLLHQYTRGYGHVRLVNALSKLYSGLVGKELNPLSDILITSGA 134
            |||...|::...:... |...:.:|:|||:.:|:..|...|:..:..|:|:|::||.::|:|.|.
Human   131 FPDFPPPDFAVEAFQH-AVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGG 194

  Fly   135 YEALYSTIMGHVDVGDEVIIIEPFFDCYEPMVKMAGGVPRFVPLKLRKTEGPI------SSADWV 193
            |.||::.....||.|||||||||||||||||..||||.|.||.||    .|||      ||::|.
Human   195 YGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLK----PGPIQNGELGSSSNWQ 255

  Fly   194 LDDAEFESLFNSKTKMIILNTPHNPIGKVFNRKELERIAELCRKWNVLCVSDEVYEWLVFDGAEH 258
            ||..|....|.|:||.::||||:||:||||:|:|||.:|.||::.:|:|::||||:|:|:||.:|
Human   256 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQH 320

  Fly   259 IRICTLPGMWDRTITLGSAGKTFSVTGWKIGWAYGPAELIRNLQMVHQNSVYTCPTPLQEGVARS 323
            |.|.:|||||:||:|:||||||||.||||:||..||..::::|:.||||||:.|||..|..||.|
Human   321 ISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAES 385

  Fly   324 FEVELARLGQPESYFLSLPRELKQKRDFMAKFLSESGMRPTIPEGGYFMLADWSPLAGKI-DLSS 387
            ||.|.....||.|||:..|:.:::.||.|.:.|...|::|.||:|.||::.|.|....|: ||..
Human   386 FEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPG 450

  Fly   388 EPDKHRDYKFTKWMTKNMGLQGIPPSAFYSEPNKHLGEDFVRYCFIKKQENLDKAAELLSKWK 450
            ..|:..|.:|.|||.||.||..||.|.|||.|::...:.::|:||:|.:..|....|.|.|||
Human   451 AVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KyatNP_650121.1 PRK08912 56..449 CDD:181580 188/399 (47%)
KYAT1NP_001274319.1 AspB 101..512 CDD:440205 193/415 (47%)

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