Protein Alignment Kyat and ALT1

DIOPT Version :10

• Sequence 1: NP_650121.1
• Gene: Kyat / 41433
• FlyBaseID: FBgn0037955
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_013190.1
• Gene: ALT1 / 850778
• SGDID: S000004079
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 518
• Identity: 115/518 - (22%)
• Similarity: 195/518 - (37%)
• Gaps: 125/518 - (24%)

  Fly     6 QLTLSAAKRS-LREQFQLQA---LRHQQTAIKMEK------FDL--------PKRLQGSTPSVWN 52
            ||||.....: |:.::.::.   :|.::...::||      ||.        |::||....:.:.
Yeast   110 QLTLEDVNENVLKAKYAVRGAIPMRAEELKAQLEKDPQSLPFDRIINANIGNPQQLQQKPLTYYR 174

  Fly    53 EYIALAMQYKPLNLGQGFPDDAAPEYVTHSL--ADIAKEQNPLLHQ-------YTRGYGHVRLVN 108
            :.::| :||..| |.|.     ..:.|...|  .|..|....|:..       |:...|    |.
Yeast   175 QVLSL-LQYPEL-LNQN-----EQQLVDSKLFKLDAIKRAKSLMEDIGGSVGAYSSSQG----VE 228

  Fly   109 ALSKLYSGLVGK----ELNPLSDILITSGAYEA---LYSTIMGHVDVGDEVIIIEPFFDCYEPMV 166
            .:.|..:..:.|    |::...||.:|:||..|   |.|......:.|  |:|..|.:..|...:
Yeast   229 GIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGPETG--VLIPIPQYPLYTATL 291

  Fly   167 KMAGGVPRFVPLKLRKTEGPISSADWVLDDAEFESLFN-------SKTKMIILNTPHNPIGKVFN 224
            .:...  :.:|..|.:..|      |..:..|.|::..       ..|.::::| |.||.|.|.:
Yeast   292 ALNNS--QALPYYLDENSG------WSTNPEEIETVVKEAIQNEIKPTVLVVIN-PGNPTGAVLS 347

  Fly   225 RKELERIAELCRKWNVLCVSDEVYEWLVFDGA--------------EHIRICTLPGMWDRTITLG 275
            .:.:.:|.|:..|:..:.::||||:..:|.|.              ||      ||.:| .:.|.
Yeast   348 PESIAQIFEVAAKYGTVVIADEVYQENIFPGTKFHSMKKILRHLQREH------PGKFD-NVQLA 405

  Fly   276 SAGKTFSVTGWKIGWAYGPAELIRNLQMVHQ-----NSVYTCPT------------PLQEGVARS 323
            |...|......:.|...|..||......:.|     .|:..||.            |..|| ..|
Yeast   406 SLHSTSKGVSGECGQRGGYMELTGFSHEMRQVILKLASISLCPVVTGQALVDLMVRPPVEG-EES 469

  Fly   324 FEVELARLGQPESYFLSLPRELKQKRDFMAKFLSESGMRPTIPEGGYFMLADWSPLAGKIDL--- 385
            ||.:.|.........::....|.:      .|.|..|:....|:|..::..       ||||
Yeast   470 FESDQAERNSIHEKLITRAMTLYE------TFNSLEGIECQKPQGAMYLFP-------KIDLPFK 521

  Fly   386 SSEPDKH----RDYKFTKWMTKNMGLQGIPPSAFYSEPNK-HLGEDFVR--YCFIKKQENLDK 441
            :.:..:|    .|..:.|.:.::.|:..:|.|.|..||.. ||...|:.  ..:|||.|:..|
Yeast   522 AVQEARHLELTPDEFYCKKLLESTGICTVPGSGFGQEPGTYHLRTTFLAPGLEWIKKWESFHK 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kyat	NP_650121.1	PRK08912	56..449	CDD:181580	102/450 (23%)
ALT1	NP_013190.1	PTZ00377	111..590	CDD:240391	114/517 (22%)