DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kyat and kyat1

DIOPT Version :9

Sequence 1:	NP_650121.1	Gene:	Kyat / 41433	FlyBaseID:	FBgn0037955	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_998524.2	Gene:	kyat1 / 791592	ZFINID:	ZDB-GENE-040426-2676	Length:	446	Species:	Danio rerio

Alignment Length:	417	Identity:	204/417 - (48%)
Similarity:	286/417 - (68%)	Gaps:	16/417 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 KRLQGSTPSVWNEYIALAMQYKPLNLGQGFPDDAAPEYVTHSLADIAKEQNPL-----LHQYTRG 100
            :||:|...::|.|:..||..||.:||||||||.:.|.::..:..      |.|     :|||||.
Zfish    34 RRLEGIDKNIWVEFTQLAADYKAVNLGQGFPDFSPPSFIQEAFC------NALTGGFRMHQYTRA 92

  Fly   101 YGHVRLVNALSKLYSGLVGKELNPLSDILITSGAYEALYSTIMGHVDVGDEVIIIEPFFDCYEPM 165
            :||..||..|:|.:|.:||:|::|:.|||::.|||:||:.|....||.||||||:|||||||:||
Zfish    93 FGHPNLVKILAKFFSRIVGREIDPMEDILVSVGAYQALFCTFQALVDEGDEVIIVEPFFDCYQPM 157

  Fly   166 VKMAGGVPRFVPLKLRKTEGP-ISSADWVLDDAEFESLFNSKTKMIILNTPHNPIGKVFNRKELE 229
            |.||||:|.:||||.|:..|| ::||||||...|..|.|.|:||.|::|||:||:|||:..:||:
Zfish   158 VMMAGGMPVYVPLKPREGRGPALTSADWVLSPEELASKFTSRTKAIVINTPNNPLGKVYQWEELQ 222

  Fly   230 RIAELCRKWNVLCVSDEVYEWLVFDGAEHIRICTLPGMWDRTITLGSAGKTFSVTGWKIGWAYGP 294
            .||:||.|.:|:|:||||||||.:|||:|::|.:|||||:||:|:||||||||.||||:|||.|.
Zfish   223 VIADLCIKHDVICISDEVYEWLTYDGAKHVKIASLPGMWERTVTIGSAGKTFSATGWKVGWAIGS 287

  Fly   295 AELIRNLQMVHQNSVYTCPTPLQEGVARSFEVELARLGQPESYFLSLPRELKQKRDFMAKFLSES 359
            ..::::|:.|||||||.|.|..||.::..|:.|....|..:|||..||..|.:||..:|..|...
Zfish   288 GHIMKHLKTVHQNSVYHCATAAQEAISVGFQREYDVFGTEDSYFHQLPITLHEKRKRLADCLKSV 352

  Fly   360 GMRPTIPEGGYFMLADWSPLAGKIDLSSEPDKHR--DYKFTKWMTKNMGLQGIPPSAFYSEPNKH 422
            |::|.:|:|||||:||.|.:  .:||:....|..  ||:|.||:.|..||..||.|||||..::.
Zfish   353 GLKPILPQGGYFMIADISNI--NVDLNDPTTKEEPYDYRFVKWLIKEKGLATIPVSAFYSPEHRD 415

  Fly   423 LGEDFVRYCFIKKQENLDKAAELLSKW 449
            ..:.::|:||:|:...|..|..:|.:|
Zfish   416 QFQKYIRFCFVKEDSTLQAAENILKQW 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kyat	NP_650121.1	PRK08912	56..449	CDD:181580	198/400 (50%)
Kyat	NP_650121.1	AAT_like	64..448	CDD:99734	194/391 (50%)
kyat1	NP_998524.2	PRK08912	43..442	CDD:181580	200/406 (49%)
kyat1	NP_998524.2	AAT_like	57..441	CDD:99734	194/391 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	428	1.000	Domainoid score	I579
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	445	1.000	Inparanoid score	I1611
OMA	1	1.010	-	-		QHG53781
OrthoDB	1	1.010	-	-		D396367at33208
OrthoFinder	1	1.000	-	-		FOG0001158
OrthoInspector	1	1.000	-	-		otm24784
orthoMCL	1	0.900	-	-		OOG6_100255
Panther	1	1.100	-	-	LDO	PTHR43807
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1782
SonicParanoid	1	1.000	-	-		X786
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870