DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kyat and Accs

DIOPT Version :9

Sequence 1:	NP_650121.1	Gene:	Kyat / 41433	FlyBaseID:	FBgn0037955	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001277711.1	Gene:	Accs / 329470	MGIID:	1919717	Length:	502	Species:	Mus musculus

Alignment Length:	421	Identity:	89/421 - (21%)
Similarity:	162/421 - (38%)	Gaps:	103/421 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 FPDDAAPEYVTHSLADIAKEQNP--------------------------LLH------QYTRGYG 102
            |.|.|...|.|:.:.:..:::||                          :||      ||....|
Mouse    74 FWDSAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLTQGDMLHVEPSLLQYPDWRG 138

  Fly   103 HVRLVNALSKLYSGLVGKELNPL--SDILITSGA---YEALYSTIMGHVDVGDEVIIIEPFFDCY 162
            |:.|...::|..| ...|...||  .::::.:|.   :.|| :|::  .:.|:.::|..|::...
Mouse   139 HLFLREEVAKFLS-FYCKSPAPLKPENVVVLNGCASLFSAL-ATVL--CEAGEALLIPTPYYGAI 199

  Fly   163 EPMVKMAGGV--------PRFVPLKLRKTEGPISSADWVLDDAEFESLFNSKTKMIILNTPHNPI 219
            ...:.:.|.|        .:...|..|..:..:...:.||.....|.:   |.|.:||..|.||:
Mouse   200 TQHIYLYGNVRLAYVYLDSKVTGLNTRPFQLTVEKLEMVLQGVSSEGV---KVKGLILINPQNPL 261

  Fly   220 GKVFNRKELERIAELCRKWNVLCVSDEVYEWLVFDGAEHIR-ICTLPGMWD--RTITLGSAGKTF 281
            |.|::.:||:.......:..:..:.||||...||:.:...| :.:|..:.|  ||..:.:..|.|
Mouse   262 GDVYSPEELQDFLRFAMRHKLHVIMDEVYMLSVFEESLGYRSVLSLERLPDPQRTHVMWATSKDF 326

  Fly   282 SVTGWKIGWAYGP----AELIRNLQMVHQNSVYTCPTPLQEGVARSFEVELARLGQPESYF--LS 340
            .::|.:.|..|..    |..:.:|...|             |::...:.::|:|.:...:.  :.
Mouse   327 GMSGLRFGVLYTENQHVATAVASLCRYH-------------GLSGLVQHQMAQLLRDHDWISQVY 378

  Fly   341 LPR---ELKQKRDFMAKFLSESGMRPTIPEG-GYFMLAD----------------WSP-LAGKID 384
            ||.   .||....::::.|...|: |.:..| |:|:..|                |.. |..|:.
Mouse   379 LPENHARLKAAHTYVSEELRALGI-PFVSRGAGFFIWVDLRKYLCKGTFEEEALLWRQFLDNKVL 442

  Fly   385 LSS-------EPDKHRDYKFTKWMTKNMGLQ 408
            |||       ||...|.....|.....:|:|
Mouse   443 LSSGKTFECKEPGWFRVVFSDKENRLRLGMQ 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kyat	NP_650121.1	PRK08912	56..449	CDD:181580	89/421 (21%)
Kyat	NP_650121.1	AAT_like	64..448	CDD:99734	89/421 (21%)
Accs	NP_001277711.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
Accs	NP_001277711.1	PLN02450	81..483	CDD:178069	86/414 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900