DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kyat and Kyat1

DIOPT Version :9

Sequence 1:	NP_650121.1	Gene:	Kyat / 41433	FlyBaseID:	FBgn0037955	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001013182.3	Gene:	Kyat1 / 311844	RGDID:	1306912	Length:	457	Species:	Rattus norvegicus

Alignment Length:	427	Identity:	204/427 - (47%)
Similarity:	287/427 - (67%)	Gaps:	6/427 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 HQQTAIKMEKFDLPKRLQGSTPSVWNEYIALAMQYKPLNLGQGFPDDAAPEYVTHSLADIAKEQN 91
            ||  ::.|.|....:||.|...::|.|:..|..:|..:||||||||.:.|::.|.:... |...|
  Rat    30 HQ--SLTMTKRLQARRLDGIDQNLWVEFGKLTKEYDVVNLGQGFPDFSPPDFATQAFQQ-ATSGN 91

  Fly    92 PLLHQYTRGYGHVRLVNALSKLYSGLVGKELNPLSDILITSGAYEALYSTIMGHVDVGDEVIIIE 156
            .:|:||||.:|:..|.|.|:..:..|:|:|::||:::|:|.|||.||::.....||.||||||:|
  Rat    92 FMLNQYTRAFGYPPLTNVLASFFGKLLGQEMDPLTNVLVTVGAYGALFTAFQALVDEGDEVIIME 156

  Fly   157 PFFDCYEPMVKMAGGVPRFVPLKLRKT-EGPI-SSADWVLDDAEFESLFNSKTKMIILNTPHNPI 219
            |.|||||||..||||.|.||.||.... :|.: :|.||.||.||..|.|..:||:::||||:||:
  Rat   157 PAFDCYEPMTMMAGGCPVFVTLKPSPAPKGKLGASNDWQLDPAELASKFTPRTKILVLNTPNNPL 221

  Fly   220 GKVFNRKELERIAELCRKWNVLCVSDEVYEWLVFDGAEHIRICTLPGMWDRTITLGSAGKTFSVT 284
            ||||:|.|||.:|.||::.:|:|:|||||:|||:||.:|:.|.:||||||||:|:|||||:||.|
  Rat   222 GKVFSRMELELVANLCQQHDVVCISDEVYQWLVYDGHQHVSIASLPGMWDRTLTIGSAGKSFSAT 286

  Fly   285 GWKIGWAYGPAELIRNLQMVHQNSVYTCPTPLQEGVARSFEVELARLGQPESYFLSLPRELKQKR 349
            |||:||..||..::::|:.|||||::.|||..|..||:.||.|....|||.||||.||:.::..|
  Rat   287 GWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMELNR 351

  Fly   350 DFMAKFLSESGMRPTIPEGGYFMLADWSPLAGKI-DLSSEPDKHRDYKFTKWMTKNMGLQGIPPS 413
            |.|.:.|...|::..|.:|.||::||.|....|: ||....|:..|.:|.|||.|||||.|||.|
  Rat   352 DHMIRSLQSVGLKLWISQGSYFLIADISDFKSKMPDLPGAEDEPYDRRFAKWMIKNMGLVGIPVS 416

  Fly   414 AFYSEPNKHLGEDFVRYCFIKKQENLDKAAELLSKWK 450
            .|:|.|::...:.::|:||:|.:..|....|.|.|||
  Rat   417 TFFSRPHQKDFDHYIRFCFVKDKATLQAMDERLRKWK 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kyat	NP_650121.1	PRK08912	56..449	CDD:181580	192/395 (49%)
Kyat	NP_650121.1	AAT_like	64..448	CDD:99734	190/386 (49%)
Kyat1	NP_001013182.3	PRK08912	58..454	CDD:181580	195/397 (49%)
Kyat1	NP_001013182.3	AAT_like	65..451	CDD:99734	190/386 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53781
OrthoDB	1	1.010	-	-		D396367at33208
OrthoFinder	1	1.000	-	-		FOG0001158
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100255
Panther	1	1.100	-	-	LDO	PTHR43807
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X786
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.790