DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment glo and esrp2

DIOPT Version :9

Sequence 1:	NP_650120.1	Gene:	glo / 41431	FlyBaseID:	FBgn0259139	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_954966.1	Gene:	esrp2 / 572992	ZFINID:	ZDB-GENE-030131-9824	Length:	736	Species:	Danio rerio

Alignment Length:	227	Identity:	74/227 - (32%)
Similarity:	119/227 - (52%)	Gaps:	22/227 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGI 81
            |.:|...:..:..:.::......|.|.| :|...:|.|||||.::.::|..|.:.:|:..|...:
Zfish   193 DPYNHKFSAFETVNYKFESGACSKTEAV-DSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVAL 256

  Fly    82 HLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHGTA- 145
            .|   ...|:..|||.|...:.|..:.|...:|..||.|||||:.||.:|    ..||:| ||:
Zfish   257 CL---NAQGRRNGEALVRFINSEHRDMALDRHKHHMGSRYIEVYKATGEE----FLKIAG-GTSN 313

  Fly   146 -----------FVVKLRGLPYAVTEQQIEEFFSGLDIKTD-REGILFVMDRRGRATGEAFVQFES 198
                       .::::||||:..|.|.:..|.......|| .||:|||....||.||:|||.|..
Zfish   314 EVAQFLSKENQMIIRMRGLPFTATPQDVLGFLGPECPVTDGTEGLLFVKYPDGRPTGDAFVLFAC 378

  Fly   199 QDDTEQALGRNREKIGHRYIEIFRSSIAEMKR 230
            ::..:.||.::::.:|.||||:|||:.||:::
Zfish   379 EEYAQNALKKHKQILGKRYIELFRSTAAEVQQ 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	25/73 (34%)
		RRM2_hnRNPH_like	146..224	CDD:240948	31/78 (40%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950
esrp2	NP_954966.1	DnaQ_like_exo	8..165	CDD:299142
		RRM_SF	225..304	CDD:302621	29/85 (34%)
		RRM2_ESRP2	309..415	CDD:241184	37/103 (36%)
		RRM3_ESRP1_ESRP2	449..529	CDD:241186
		WWbp	<572..658	CDD:304964
		RRM_hnRNPH_ESRPs_RBM12_like	661..732	CDD:240700
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590307
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.800