DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment glo and Esrp1

DIOPT Version :9

Sequence 1:	NP_650120.1	Gene:	glo / 41431	FlyBaseID:	FBgn0259139	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_006237938.1	Gene:	Esrp1 / 500409	RGDID:	1560481	Length:	681	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	78/252 - (30%)
Similarity:	125/252 - (49%)	Gaps:	57/252 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DEDDQYNEDGGGKIENVGE--------------------SPKF----------------VRLRGL 56
            :::|..:..|..::|::|.                    :.||                ||.|||
  Rat   168 EKNDSMSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKTELIDGNTVVRARGL 232

  Fly    57 PWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRY 121
            ||.::.::|..|.:.:|:..|.|.:.|   ...|:..|||.|...|:|..:.|.:.:|..||.||
  Rat   233 PWQSSDQDIARFFKGLNIAKGGAALCL---NAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRY 294

  Fly   122 IEVFTATPKEAKEAMRKISGHGTA------------FVVKLRGLPYAVTEQQIEEFF-SGLDIKT 173
            |||:.||    .|...||:| ||:            .:|::||||:..|.:::..|| ....|..
  Rat   295 IEVYKAT----GEDFLKIAG-GTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITG 354

  Fly   174 DREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKR 230
            .:||||||....||.||:|||.|..::..:.||.::::.:|.||||:|||:.||:::
  Rat   355 GKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQ 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	28/73 (38%)
		RRM2_hnRNPH_like	146..224	CDD:240948	32/78 (41%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950
Esrp1	XP_006237938.1	DnaQ_like_exo	29..168	CDD:299142	78/252 (31%)
		RRM1_ESRP1	221..305	CDD:241180	32/90 (36%)
		RRM	<285..473	CDD:223796	51/132 (39%)
		RRM2_ESRP1	310..418	CDD:241183	38/103 (37%)
		RRM3_ESRP1_ESRP2	444..524	CDD:241186
		RRM	<446..>520	CDD:223796
		RRM_SF	634..>672	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349084
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.800