DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment glo and esrp1

DIOPT Version :9

Sequence 1:	NP_650120.1	Gene:	glo / 41431	FlyBaseID:	FBgn0259139	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001005057.1	Gene:	esrp1 / 448608	XenbaseID:	XB-GENE-985138	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	79/238 - (33%)
Similarity:	126/238 - (52%)	Gaps:	37/238 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FNYGQQGNGDNFNDDSNQQQDEDDQYNEDGG--GKIENVGESPKFVRLRGLPWSATHKEILDFLE 70
            :||       .|:|      .|...|..:.|  .|:|.:.:: ..:|.|||||.::.::|..|.:
Frog   197 YNY-------KFSD------PERVNYKFESGTCSKLEIIDDN-TIIRARGLPWQSSDQDIARFFK 247

  Fly    71 NVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEA 135
            .:|:..|.|.:.|   ...|:..|||.|...|:|..:.|.:.:|..||:|||||:.||    .|.
Frog   248 GLNIAKGGAALCL---NAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKAT----GED 305

  Fly   136 MRKISGHGTA------------FVVKLRGLPYAVTEQQIEEFF-SGLDIKTDREGILFVMDRRGR 187
            ..||:| ||:            .:|::||||:..|.:::..|| ....:...:||||||.....|
Frog   306 FLKIAG-GTSNEVAQFLSKENQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNR 369

  Fly   188 ATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKR 230
            .||:|||.|..::..:.||.:::|.:|.||||:|||:.||:::
Frog   370 PTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQ 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	27/73 (37%)
		RRM2_hnRNPH_like	146..224	CDD:240948	31/78 (40%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950
esrp1	NP_001005057.1	DnaQ_like_exo	8..>146	CDD:385652
		RRM1_ESRP1	222..306	CDD:241180	31/91 (34%)
		RRM2_ESRP1	311..419	CDD:241183	37/103 (36%)
		RRM3_ESRP1_ESRP2	445..525	CDD:241186
		RRM_SF	638..>675	CDD:388407
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910