DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment glo and fus

DIOPT Version :9

Sequence 1:	NP_650120.1	Gene:	glo / 41431	FlyBaseID:	FBgn0259139	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_524691.1	Gene:	fus / 44095	FlyBaseID:	FBgn0023441	Length:	967	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	83/225 - (36%)
Similarity:	125/225 - (55%)	Gaps:	26/225 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 EDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVE 99
            |.|...|::..:....||.|||||.::.::|..|...:||..|  |:.|..|.: |:..|||.:.
  Fly   265 EPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKG--GVALCLSPL-GRRNGEALIR 326

  Fly   100 VASQEDVEEARKLNKASMGHRYIEVFTATPKE--------AKEAMRKISGHGTAFVVKLRGLPYA 156
            ...||..:.|.|.:|..:|.|||||:.|:.::        :.||...:| .|...::::|||||.
  Fly   327 FVCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFLS-KGAQVIIRMRGLPYD 390

  Fly   157 VTEQQIEEFFSGLD-----IKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHR 216
            .|.:|:.:||:..|     :....||:|||....|||||:|||.|.::.|..:||||:||.||.|
  Fly   391 ATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQR 455

  Fly   217 YIEIFRSSIAEMKRATG---------AGGG 237
            |||:|||:.||:::...         :|||
  Fly   456 YIELFRSTTAEVQQVLNRSMDPKNYESGGG 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	29/73 (40%)
		RRM2_hnRNPH_like	146..224	CDD:240948	39/82 (48%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950
fus	NP_524691.1	DnaQ_like_exo	13..194	CDD:299142
		RRM1_Fusilli	280..359	CDD:241182	31/81 (38%)
		RRM2_Fusilli	363..462	CDD:241185	42/99 (42%)
		RRM3_Fusilli	545..629	CDD:241187
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461341
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4211
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D392876at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm959
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13976
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850