Protein Alignment glo and hnrnph1

DIOPT Version :9

• Sequence 1: NP_650120.1
• Gene: glo / 41431
• FlyBaseID: FBgn0259139
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_991247.1
• Gene: hnrnph1 / 402984
• ZFINID: ZDB-GENE-040426-1856
• Length: 403
• Species: Danio rerio
• Alignment Length: 561
• Identity: 150/561 - (26%)
• Similarity: 224/561 - (39%)
• Gaps: 218/561 - (38%)

  Fly    36 DGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEV 100
            ||.|.:         ||:||||||.:..|:..|.....:.:....||...:| :|:.:|||:||.
Zfish     3 DGEGFV---------VRVRGLPWSCSVDEVQRFFSECKIASNGTSIHFTYTR-EGRPSGEAFVEF 57

  Fly   101 ASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMR-------KISGHGTAFVVKLRGLPYAVT 158
            .|:||::.|.|.::.:|||||:|||.:...|....::       :..|.|   :|:|||||:..:
Zfish    58 ESEEDLKIAVKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNCPETGGDG---LVRLRGLPFGCS 119

  Fly   159 EQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRS 223
            :::|.:||:||:|..:  ||...:|.:||:||||||||.|||..|:||.:::|:|||||||||:|
Zfish   120 KEEIVQFFAGLEIVPN--GITLPVDFQGRSTGEAFVQFASQDIAEKALKKHKERIGHRYIEIFKS 182

  Fly   224 SIAEMKRATGAGGGVGG--RPGPYDIRDRGANRGGNDFGGGRNDWGNNGNFGVGANNMLGFNNLP 286
            |.||::........|.|  ||.|||..           ||||                 |:|::
Zfish   183 SRAEVRTHYEPQRKVMGMQRPSPYDRP-----------GGGR-----------------GYNSM- 218

  Fly   287 SLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFG 351
                                                                      ..|.:|.
Zfish   219 ----------------------------------------------------------GRGVSFE 225

  Fly   352 GNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNN 416
            ....||                         :||:|..| ::|.:|.|::|
Zfish   226 RMRRGG-------------------------YGGDGRYG-DSGSSFQSTTG-------------- 250

  Fly   417 NGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYY 481
                                                                            :
Zfish   251 ----------------------------------------------------------------H 251

  Fly   482 TIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGS 546
            .:|||||||.:.|.|::.||.|:.|..|.:.....|..:|.||..|.|:||:..||.:.:..|..
Zfish   252 CVHMRGLPYRATETDIYNFFSPLNPVRVHLEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQH 316

  Fly   547 RYIELFYDGKTRGLNGGEHGGGNGGGGMGNNGG-GNFSRRI 586
            ||:|||.:....|.:||.  ||...|||||... |:.|:::
Zfish   317 RYVELFLNSTAGGGSGGY--GGQMMGGMGNQSSYGHSSQQM 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	30/73 (41%)
		RRM2_hnRNPH_like	146..224	CDD:240948	41/77 (53%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950	30/73 (41%)
hnrnph1	NP_991247.1	RRM	<5..>74	CDD:223796	25/78 (32%)
		RRM1_hnRNPH_hnRNPH2_hnRNPF	6..84	CDD:241173	33/87 (38%)
		RRM	<57..>168	CDD:223796	47/115 (41%)
		RRM_SF	89..184	CDD:302621	44/99 (44%)
		RRM3_hnRNPH_hnRNPH2_hnRNPF	251..326	CDD:241178	30/74 (41%)
		RRM	<251..>307	CDD:223796	22/55 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590311
Domainoid	1	1.000	78	1.000	Domainoid score	I8693
eggNOG	1	0.900	-	-		E1_KOG4211
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D392876at33208
OrthoFinder	1	1.000	-	-		FOG0000855
OrthoInspector	1	1.000	-	-		otm25364
orthoMCL	1	0.900	-	-		OOG6_102542
Panther	1	1.100	-	-	O	PTHR13976
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4231
SonicParanoid	1	1.000	-	-		X436
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.780