Protein Alignment glo and RBM12B

DIOPT Version :10

• Sequence 1: NP_650120.1
• Gene: glo / 41431
• FlyBaseID: FBgn0259139
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_976324.2
• Gene: RBM12B / 389677
• HGNCID: 32310
• Length: 1001
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 59/236 - (25%)
• Similarity: 94/236 - (39%)
• Gaps: 73/236 - (30%)

  Fly    51 VRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKA 115
            :||.|||:.|...:|..|...:.:.:|  |:|::     |...|||::..|:.||...|...:..
Human     5 IRLLGLPFIAGPVDIRHFFTGLTIPDG--GVHII-----GGEIGEAFIIFATDEDARRAISRSGG 62

  Fly   116 SMGHRYIEVFTATPKEAKEAM---------RKISGHGTAFV---------VK------------- 149
            .:....:|:|.::..|.::.:         |...|.||:.|         ||
Human    63 FIKDSSVELFLSSKAEMQKTIEMKRTDRVGRGRPGSGTSGVDSLSNFIESVKEEASNSGYGSSIN 127

  Fly   150 -------------------------------LRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMD 183
                                           ||||||.|.|..:..|||||.:    :|::|:..
Human   128 QDAGFHTNGTGHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV----DGVIFLKH 188

  Fly   184 RRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSS 224
            ..||..|:|.|:|.|..|....|..:|..:|.|:||:.:.|
Human   189 HDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_hnRNPH_ESRPs_RBM12_like	50..125	CDD:409699	20/73 (27%)
		RRM2_hnRNPH_CRSF1_like	146..224	CDD:409927	32/130 (25%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:409929
RBM12B	NP_976324.2	RRM1_RBM12B	2..80	CDD:410139	22/81 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	119..147		0/27 (0%)
		RRM2_RBM12B	153..238	CDD:410140	30/81 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	247..278
		RRM3_RBM12B	284..363	CDD:409935
		RRM4_RBM12B	400..475	CDD:410142
		COG4253	498..>803	CDD:443395
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	544..587
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	631..882
		PHA03321	<689..915	CDD:223041
		RRM5_RBM12B	925..1001	CDD:410144