DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment glo and Rbm12b

DIOPT Version :9

Sequence 1:	NP_650120.1	Gene:	glo / 41431	FlyBaseID:	FBgn0259139	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	XP_006237956.2	Gene:	Rbm12b / 313069	RGDID:	1307658	Length:	843	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	56/235 - (23%)
Similarity:	96/235 - (40%)	Gaps:	72/235 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 VRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKA 115
            :||:|||:.|...:|..|.:.:.:.:|  |:|::     |...|||::..|:.||...|...:..
  Rat     5 IRLQGLPFIAGPVDIRHFFKGLTIPDG--GVHVI-----GGKAGEAFIIFATDEDARRAISRSGG 62

  Fly   116 SMGHRYIEVFTATPKEAKEAM---------------------------------RKISGHGTA-- 145
            .:....:|:|.::..|.::.:                                 .:.||:|:|
  Rat    63 FIKDSSVELFLSSKVEMQKTIDMKRSARVGRGRPGPEASGVGNMYHFIDALKEEERYSGYGSAVN 127

  Fly   146 ----FVVK----------------------LRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDR 184
                |.:.                      ||||||.|.|..:..|||||.:    :|::.:...
  Rat   128 PDAGFHINGTGLDLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV----DGVILLKHH 188

  Fly   185 RGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSS 224
            .||..|:|.|:|.|..|....|..:|..:|.|:||:.:.|
  Rat   189 DGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	20/73 (27%)
		RRM2_hnRNPH_like	146..224	CDD:240948	29/99 (29%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950
Rbm12b	XP_006237956.2	RRM_SF	2..80	CDD:418427	22/81 (27%)
		RRM2_RBM12B	152..237	CDD:410140	29/81 (36%)
		RRM_SF	283..362	CDD:418427
		RRM	<367..581	CDD:223796
		RRM4_RBM12B	401..476	CDD:410142
		PTZ00465	<619..703	CDD:185644
		RRM_SF	767..843	CDD:418427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349098
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840