Protein Alignment glo and Grsf1

DIOPT Version :10

• Sequence 1: NP_650120.1
• Gene: glo / 41431
• FlyBaseID: FBgn0259139
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_848815.2
• Gene: Grsf1 / 231413
• MGIID: 106479
• Length: 479
• Species: Mus musculus
• Alignment Length: 545
• Identity: 126/545 - (23%)
• Similarity: 193/545 - (35%)
• Gaps: 231/545 - (42%)

  Fly    38 GGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVAS 102
            |.::::|    ..:|.:|||||.|.:::|:|..:..:.|...|||.:.:| |||..|:|.:|:.|
Mouse   142 GDEVDDV----YLIRAQGLPWSCTVEDVLNFFSDCRIRNSENGIHFLLNR-DGKRRGDALIEMES 201

  Fly   103 QEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHGTAF----VVKLRGLPYAVTEQQIE 163
            ::||::|.:.::..||.||:||:....::....|:.:....:..    ||:||||||:..|:.|.
Mouse   202 EQDVQKALEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKPSPVLSDGVVRLRGLPYSCNEKDIV 266

  Fly   164 EFFSGLDIKTDREGILFVMDRRG-RATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAE 227
            :||:||:|    ..|.||||.|| |.||||:||||..:...|||.::||:||:||||||.|...|
Mouse   267 DFFAGLNI----VDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHREEIGNRYIEIFPSRRNE 327

  Fly   228 MKRATGAGGG---VGGRPGPY---------------DIRDRGANRGGNDFGGGRNDWGNNGNFGV 274
            ::...|:..|   ....|..|               |||...|.....:.
Mouse   328 VRTHVGSHKGKKMTSSPPTKYITEPEVVFEEHEVNEDIRPMTAFESDKEI--------------- 377

  Fly   275 GANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNF 339
                     .||..|:.
Mouse   378 ---------ELPKEMSE------------------------------------------------ 385

  Fly   340 GNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVG 404
                                       ..|..| :||.....:|
Mouse   386 ---------------------------KLPEAV-DFGTLPSLHF--------------------- 401

  Fly   405 NFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGP 469
                                                                             
Mouse   402 ----------------------------------------------------------------- 401

  Fly   470 IGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQ 534
                         :||||||:.:...|:..||.|::|..:.:.|:..|..:|.||.:|||:||:.
Mouse   402 -------------VHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFDTHEDAV 453

  Fly   535 VAMKRHREQMGSRYIELFYDGKTRG 559
            .||.:.|..:..||||||.:...:|
Mouse   454 AAMLKDRSHVQHRYIELFLNSCPKG 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_hnRNPH_ESRPs_RBM12_like	50..125	CDD:409699	29/74 (39%)
		RRM2_hnRNPH_CRSF1_like	146..224	CDD:409927	44/82 (54%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:409929	30/73 (41%)
Grsf1	NP_848815.2	RRM1_GRSF1	148..226	CDD:410129	31/82 (38%)
		RRM2_GRSF1	248..324	CDD:409928	44/79 (56%)
		RRM3_GRSF1	400..474	CDD:410132	31/172 (18%)