DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment glo and Esrp1

DIOPT Version :9

Sequence 1:	NP_650120.1	Gene:	glo / 41431	FlyBaseID:	FBgn0259139	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_918944.2	Gene:	Esrp1 / 207920	MGIID:	1917326	Length:	681	Species:	Mus musculus

Alignment Length:	213	Identity:	78/213 - (36%)
Similarity:	119/213 - (55%)	Gaps:	24/213 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 YNEDGG--GKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGE 95
            |..:.|  .|:|.:.:| ..||.|||||.::.::|..|.:.:|:..|.|.:.|   ...|:..||
Mouse   208 YKFESGTCSKMELIDDS-TVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCL---NAQGRRNGE 268

  Fly    96 AYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHGTA------------FVV 148
            |.|...|:|..:.|.:.:|..||.|||||:.||    .|...||:| ||:            .:|
Mouse   269 ALVRFVSEEHRDLALQRHKHHMGTRYIEVYKAT----GEDFLKIAG-GTSNEVAQFLSKENQVIV 328

  Fly   149 KLRGLPYAVTEQQIEEFF-SGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREK 212
            ::||||:..|.:::..|| ....|...:||||||....||.||:|||.|..::..:.||.:::|.
Mouse   329 RMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKEL 393

  Fly   213 IGHRYIEIFRSSIAEMKR 230
            :|.||||:|||:.||:::
Mouse   394 LGKRYIELFRSTAAEVQQ 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	28/73 (38%)
		RRM2_hnRNPH_like	146..224	CDD:240948	33/78 (42%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950
Esrp1	NP_918944.2	DnaQ_like_exo	29..>145	CDD:299142
		RRM1_ESRP1	221..305	CDD:241180	33/91 (36%)
		RRM	<285..473	CDD:223796	52/132 (39%)
		RRM2_ESRP1	310..418	CDD:241183	39/103 (38%)
		RRM3_ESRP1_ESRP2	444..524	CDD:241186
		RRM	<446..>520	CDD:223796
		RRM_SF	634..>672	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845680
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.800