Protein Alignment glo and hrpf-1

DIOPT Version :9

• Sequence 1: NP_650120.1
• Gene: glo / 41431
• FlyBaseID: FBgn0259139
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_740877.1
• Gene: hrpf-1 / 172395
• WormBaseID: WBGene00020936
• Length: 549
• Species: Caenorhabditis elegans
• Alignment Length: 589
• Identity: 143/589 - (24%)
• Similarity: 235/589 - (39%)
• Gaps: 135/589 - (22%)

  Fly    51 VRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKA 115
            |:.|||||.||.:|:.||..|    ||...:.:  .|.:|:.:|:|.|...::||...|.|.::.
 Worm     7 VQCRGLPWEATEQELRDFFGN----NGIESLEI--PRRNGRTSGDAKVVFTNEEDYNNALKKDRE 65

  Fly   116 SMGHRYIEVFTATPKEAKEAMRKISG---------------------------HGTAFVVKLRGL 153
            .:|.||||||.|.....:...|...|                           .|...:|:||||
 Worm    66 HLGSRYIEVFPAGGAPTRRGDRGERGDRGDRDHYRSRGAPPRDRYSDRGGPRSSGPDSIVRLRGL 130

  Fly   154 PYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYI 218
            |::||.:.|.:|.:.|.|.  |:|||....:|.|..|||:|.||:.:..:.|..|:.:.||||||
 Worm   131 PFSVTSRDISDFLAPLPIV--RDGILLPDQQRARPGGEAYVCFETMESVQIAKQRHMKNIGHRYI 193

  Fly   219 EIFRSSIAEMKRATGAGGGVGGR--PGPYDIRDRGANRGGND-FGGGRNDWGNNGNFGVGA--NN 278
            |:|.::..::.|..........|  |.|:....:.|.||..| :....:.:.|..::...|  .:
 Worm   194 EVFEATHRDLSRFAEENDLRVPRFGPPPFASAPQTAPRGAYDPYSQPTDPYRNATDYRRAAEPED 258

  Fly   279 MLGFNNLPSLMNSG----------------NFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSG 327
            ....:..||:.:.|                ::.:.|..:.|.:.|.:..:.:.::  |...|...
 Worm   259 PYARSRAPSVQDYGVRASYDPYTQPAAPVSSYPSQQQPSAGYYDNYAPKTAYESY--GRERGPDP 321

  Fly   328 NFGNDSGNS------------------GNFGNFGNNG------GGNFGGNNNGGGGFNSGNNFNS 368
            ....|..:|                  ..:..:|...      ||: ||..:.|||...|....:
 Worm   322 RDVRDPRDSRMPDPRDSRALSDPYAAESRYSEYGYESREPYWRGGS-GGPPSIGGGVGGGGAPLA 385

  Fly   369 PGGVNNF--GNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGN--FG 429
            |.|.:.:  |.:..:..||.||.                 .|:...|:    .:|:.|:.:  :.
 Worm   386 PTGRDPYSVGESWANGAGGPGGP-----------------PPVSSDRD----RYGSGGYASEPYA 429

  Fly   430 GNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDI-----EYYTIHMRGLP 489
            ...             .||....|.:|..:.......  |.|..|..|.     :::.:.|||:|
 Worm   430 QRE-------------AGGAMRRSEYGRPDDRYSKPE--PYGYSRDRDYGAPQNQHFVLRMRGVP 479

  Fly   490 YTSFENDVFKFFEPIRPANVRI----NYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIE 550
            :.:.|.||:.||.||||..|.:    .:.:.   ||.|...|...:|...|:.:.::.||.||||
 Worm   480 FRASEADVYDFFHPIRPNQVELLRDHQFQRP---SGDARVIFYNRKDYDDALMKDKQYMGERYIE 541

  Fly   551 LFYD 554
            :..|
 Worm   542 MIPD 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
glo	NP_650120.1	RRM_SF	51..125	CDD:302621	28/73 (38%)
		RRM2_hnRNPH_like	146..224	CDD:240948	34/77 (44%)
		RRM3_hnRNPH_CRSF1_like	481..555	CDD:240950	27/78 (35%)
hrpf-1	NP_740877.1	RRM_hnRNPH_ESRPs_RBM12_like	7..75	CDD:240700	28/73 (38%)
		RRM	<10..183	CDD:223796	58/180 (32%)
		RRM	<98..313	CDD:223796	51/216 (24%)
		RRM_SF	123..199	CDD:302621	34/77 (44%)
		RRM_hnRNPH_ESRPs_RBM12_like	472..542	CDD:240700	25/72 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I3219
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102542
Panther	1	1.100	-	-	O	PTHR13976
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4231
SonicParanoid	1	1.000	-	-		X436
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.990