| Sequence 1: | NP_788639.1 | Gene: | ClC-a / 41428 | FlyBaseID: | FBgn0051116 | Length: | 1193 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_037279.1 | Gene: | Clcn1 / 25688 | RGDID: | 2360 | Length: | 994 | Species: | Rattus norvegicus |
| Alignment Length: | 1044 | Identity: | 404/1044 - (38%) |
|---|---|---|---|
| Similarity: | 574/1044 - (54%) | Gaps: | 203/1044 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 72 PKIKSHAFYPCPP---PAENA-------RDSDSSDDDDPIGYIDTLMYGRYTKDLGEFAKDEARK 126
Fly 127 LKILEKRRKQEDKQRNKELLGK-HSTRAKRVSSWIWRHTVARLGEDWVFLALLGIIMALLSFIMD 190
Fly 191 KGISICTNARIWLYRDLTSQPFVQYIAWVSLPVCLILFSAGFVHLIAPQSIGSGIPEMKTILRGV 255
Fly 256 QLKEYLTFKTLVAKVIGLTATLGSGMPLGKEGPFVHIASIVAQLLSKLVTSFQGIYENESRNSEM 320
Fly 321 LAAACAVGVGACFAAPVGGVLFSIEVTTTYFAVRNYWRGFFAAVCGATVFRLLAVWFQNADTVRA 385
Fly 386 LFLTNFTTEFPFDPQELFVFALIGLVCGLGGASYVWVHRRYVLFMRSNKRMNKFLQKNRFLYPGF 450
Fly 451 LALLVSSISFPLGTGQFLAGELSTHEQVTQLFSNFTWSR---DDLTVEQAAVVTHWMTSYTSVFG 512
Fly 513 NLVIYTLFTFVVSIIASTIPVPSGMFIPVFKIGAGFGRLVGEFMAVTFPHGVRYGGRLSPIMPGG 577
Fly 578 YAVVGAAAFSGSVTHTVSVAVIIFEMTGQITHVVPVMIAVLVANAVAALLQPSIYDSIILIKKLP 642
Fly 643 YLPDLLPSSSGMYSIFVEDFMVRDVKYIWHGISYQKLKEVLKLNKTLRSLPLVDSPDNMILLGSV 707
Fly 708 QRYELIKMIEKHIGREKRMEVAQKWQKEAQERALEEEKKKQEVELKMRRPSRFEVLPAPDILSLR 772
Fly 773 QIANDEMLPPKKRAETMHGSLAPRKSILKKTNSFNLKTYAQPMGHSPSITPYTTITGNSEFRIRS 837
Fly 838 AFEAIFKKSTTLQDVQPDPETGSLSPAASNHEVEVPRTPSTPGVSKKVQLPAQSNWDFVTDQIML 902
Fly 903 QVNPISTESNKMPAEKDFTDKALSNNG--DSSKQSPSIKFKANKVADVNRSP-QTAKRCSKIRFA 964
Fly 965 NEVGVNGSPTRTKCKIKPENVLGYSIEDVDETTNPESLAESIQKPKSVRLPRERVIDMSPEDQKQ 1029
Fly 1030 WELEEMLKPIDLQKANVHIDPSPFQLVERTSILKVHSLFSMVGINHAYVTKIGRLVGVVGLKELR 1094
Fly 1095 KAIE 1098 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ClC-a | NP_788639.1 | ClC_1_like | 171..646 | CDD:239655 | 264/477 (55%) |
| Voltage_CLC | 227..615 | CDD:279048 | 218/390 (56%) | ||
| CBS_pair_EriC_assoc_euk_bac | 1000..1096 | CDD:239964 | 36/95 (38%) | ||
| Clcn1 | NP_037279.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 37..61 | 5/28 (18%) | |
| ClC_1_like | 117..592 | CDD:239655 | 264/477 (55%) | ||
| Voltage_CLC | 170..571 | CDD:279048 | 226/403 (56%) | ||
| Selectivity filter part_1. /evidence=ECO:0000250 | 188..192 | 3/3 (100%) | |||
| Selectivity filter part_2. /evidence=ECO:0000250 | 230..234 | 3/3 (100%) | |||
| Selectivity filter part_3. /evidence=ECO:0000250 | 482..486 | 2/3 (67%) | |||
| CBS_pair | 610..>665 | CDD:301603 | 26/55 (47%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 710..769 | 21/97 (22%) | |||
| CBS_pair_EriC_assoc_euk_bac | <827..875 | CDD:239964 | 27/47 (57%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 880..923 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 965..994 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 499 | 1.000 | Domainoid score | I337 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0038 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 775 | 1.000 | Inparanoid score | I505 |
| OMA | 1 | 1.010 | - | - | QHG52624 | |
| OrthoDB | 1 | 1.010 | - | - | D1131873at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002718 | |
| OrthoInspector | 1 | 1.000 | - | - | otm46333 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103492 | |
| Panther | 1 | 1.100 | - | - | O | PTHR45720 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X544 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.880 | |||||