Sequence 1: | NP_788639.1 | Gene: | ClC-a / 41428 | FlyBaseID: | FBgn0051116 | Length: | 1193 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001344031.1 | Gene: | Clcn4 / 12727 | MGIID: | 104571 | Length: | 747 | Species: | Mus musculus |
Alignment Length: | 742 | Identity: | 212/742 - (28%) |
---|---|---|---|
Similarity: | 323/742 - (43%) | Gaps: | 178/742 - (23%) |
- Green bases have known domain annotations that are detailed below.
Fly 133 RRKQEDKQRNKELLGKHSTRAKRVSSWIWRHTVARLGEDWVFLALLGIIMALLSFIMDKGI---- 193
Fly 194 ----SICTNARIWLYRD--------------------------LTSQP---------FVQYIAWV 219
Fly 220 SLPVCLILFSAGFVHLIAPQSIGSGIPEMKTILRGVQLKEYLTFKTLVAKVIGLTATLGSGMPLG 284
Fly 285 KEGPFVHIASIVAQLLSKLVTSFQGIYENESRNSEMLAAACAVGVGACFAAPVGGVLFSIEVTTT 349
Fly 350 YFAVRNYWRGFFAAVCGATVFRLLAVWFQNADTVRALFLTNFTTEFPFDPQELFVFALIGLVCGL 414
Fly 415 GGASY-----VWVHRRYVLFMRSNKRMNKFLQKNRFLYPGFLALLVSSISFPLG-----TGQFLA 469
Fly 470 GELSTHEQVTQLFS-----------------NFTWSRDDLTVEQAAVVTHWMTSYTSVFGNLVIY 517
Fly 518 TLFTFVVSIIASTIPVPSGMFIPVFKIGAGFGRLVG---EFMA------VTFPHGVRYGGRLSPI 573
Fly 574 MPGGYAVVGAAAFSGSVTH-TVSVAVIIFEMTGQITHVVPVMIAVLVANAVA-ALLQPSIYDSII 636
Fly 637 LIKKLPYL------------PDLLPSSSG--MYSIFVEDFM-VRDVKYIWHGISYQKLKEVLKLN 686
Fly 687 KTLRSLPLVDSPDNMILLGSVQRYELIKMIEKHIGREKRMEVAQKWQKEAQERALEEEKKKQEVE 751
Fly 752 LKMRRPSRFEVLPA--PDILSLRQIAN 776 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ClC-a | NP_788639.1 | ClC_1_like | 171..646 | CDD:239655 | 170/567 (30%) |
Voltage_CLC | 227..615 | CDD:279048 | 144/424 (34%) | ||
CBS_pair_EriC_assoc_euk_bac | 1000..1096 | CDD:239964 | |||
Clcn4 | NP_001344031.1 | Required for localization in the endoplasmic reticulum. /evidence=ECO:0000250|UniProtKB:P51793 | 1..50 | 7/30 (23%) | |
ClC_3_like | 65..571 | CDD:239656 | 166/545 (30%) | ||
Selectivity filter part_1. /evidence=ECO:0000250 | 167..171 | 3/3 (100%) | |||
Selectivity filter part_2. /evidence=ECO:0000250 | 209..213 | 3/3 (100%) | |||
Selectivity filter part_3. /evidence=ECO:0000250 | 454..458 | 2/3 (67%) | |||
CBS_pair_voltage-gated_CLC_euk_bac | 582..732 | CDD:341367 | 35/139 (25%) | ||
CBS repeat | 588..683 | CDD:341367 | 32/129 (25%) | ||
Required for localization in the endoplasmic reticulum. /evidence=ECO:0000250|UniProtKB:P51793 | 654..683 | 8/31 (26%) | |||
CBS repeat | 689..731 | CDD:341367 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0038 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |