DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sbf and mtmr9

DIOPT Version :9

Sequence 1:NP_477401.2 Gene:Sbf / 41427 FlyBaseID:FBgn0025802 Length:1993 Species:Drosophila melanogaster
Sequence 2:NP_001038535.1 Gene:mtmr9 / 565063 ZFINID:ZDB-GENE-040724-223 Length:549 Species:Danio rerio


Alignment Length:454 Identity:109/454 - (24%)
Similarity:179/454 - (39%) Gaps:145/454 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1132 LEDGDEFETQNNAMPRLLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISNANTSYATCRSYPA 1196
            :|||.:......|.      ||:|.|.:     :|             |:|..|..::.|.|||:
Zfish   120 IEDGWQLFVPEEAF------KDLESMTD-----EW-------------RLSEVNKDFSVCPSYPS 160

  Fly  1197 IIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRH-ANGALLIRGGQPNSKSVIGMLKNTTGSTTNAH 1260
            ::..|....|.:::.......|.|.|:.::.| .||.:::|..||           .||  ||  
Zfish   161 LLTVPKDIDDESLIKAASFRHGGRFPVLSYYHKKNGMVMMRAAQP-----------LTG--TN-- 210

  Fly  1261 HDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELSRKHKNNL 1325
                                                      |....:|.:.:            
Zfish   211 ------------------------------------------GRRCKEDEKLI------------ 221

  Fly  1326 DISDGNKSSQGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIPVDYPDIRQ 1390
                 |.:...||.|.:...            |..|:.::::|:..   .|..:   .:||..|:
Zfish   222 -----NATLCAGKRGYIIDT------------RTIAVAQQAKARGG---GFEQE---ANYPQWRR 263

  Fly  1391 SRPAFK----------KLIRACM-PSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLID 1444
            ...|.:          ||:.||. .|||.:.     :...:|.|:|...:..::..:......||
Zfish   264 IHKAIERSNILQESLIKLVEACNDQSHNMDR-----WLSKLEASNWQSHVKEILTTACLAAQCID 323

  Fly  1445 LQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHR------SNL 1503
            .:.:||::...:|:|.|.|::|:||:.|||..|::.||..|:|:|||..||.|..|      ||.
Zfish   324 REGASVLVHGSEGTDSTLQVTSLAQIILDPACRTIRGFEALIEREWLQAGHPFQQRCAQSAYSNG 388

  Fly  1504 KPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERS 1567
            ||.      :.||.||.|||.|.|:.||||.:|:|::.:|..|..|:.:.:|.|||.:...||:
Zfish   389 KPR------SEAPVFLLFLDCVWQILRQFPCSFQFSESFLIMLFEHTYASQFGTFLGNSVAERA 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SbfNP_477401.2 uDENN 1..91 CDD:214824
DENN 142..325 CDD:280329
dDENN 384..452 CDD:129037
SBF2 585..807 CDD:289132
PH-GRAM_MTMR5_MTMR13 933..1047 CDD:275396
Myotub-related 1161..1565 CDD:284109 99/421 (24%)
C1 1791..1838 CDD:237996
PH_Sbf1_hMTMR5 1888..1993 CDD:269941
PH 1891..1992 CDD:278594
mtmr9NP_001038535.1 PH-GRAM_MTMR9 1..97 CDD:275398
Myotub-related 108..444 CDD:284109 107/450 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170590776
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.840

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