Protein Alignment Sbf and mtm1

DIOPT Version :9

• Sequence 1: NP_477401.2
• Gene: Sbf / 41427
• FlyBaseID: FBgn0025802
• Length: 1993
• Species: Drosophila melanogaster
• Sequence 2: NP_001032773.2
• Gene: mtm1 / 560881
• ZFINID: ZDB-GENE-051113-128
• Length: 639
• Species: Danio rerio
• Alignment Length: 760
• Identity: 180/760 - (23%)
• Similarity: 285/760 - (37%)
• Gaps: 283/760 - (37%)

  Fly   929 LLPGEDLVTDHLRCFLMPDGREDETQCLIPAEGALFLTNYRVIFKGSPCDPLFCEQVIVRTFPIA 993
            |||||:.|.|....::.|..        ...:|.:|:||||:.||.:.     .|..:....|:.
Zfish    70 LLPGEERVIDKDIIYICPYN--------AAVKGKVFITNYRLYFKNTD-----SETPVTLNIPLG 121

  Fly   994 SLLKEKKISVLYLAHLDQTLTEGLQLRSSSFQLIKVAFDPEVTPEQIESFRKILSKARHP-FDEF 1057
            .:.:.:|:.             |...|..:      ::..|:|.:.:.:.|..|.:..|. .|.|
Zfish   122 VISRVEKMG-------------GASSRGEN------SYGLEITCKDMRNLRFALKQEGHSRRDIF 167

  Fly  1058 EY---FAFQ-SYGTMLQGVAPLKTKEKYSTLKGFAKKTLLRGAKKAGFKQKQQTKRKLVSDYDYG 1118
            |.   :||. |:|..|   ....::|||.
Zfish   168 EIIFKYAFPLSHGMQL---FAFLSQEKYE------------------------------------ 193

  Fly  1119 SADAQETQSIDDELEDGDEFETQNNAMPRLLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISN 1183
                :...::.:.||     |.:...:|.                .:|             |::.
Zfish   194 ----ENGWNVYEALE-----EYRRQGLPN----------------NEW-------------RVTF 220

  Fly  1184 ANTSYATCRSYPAIIVAPVQCSDAAIMHL----GRCFKGQRIPLPTWRH-ANGALLIRGGQPNSK 1243
            .|.:|..|.:||.|:|.|.:.::..:..:    .||    |||:.:|.| .|.|::.|..||
Zfish   221 INKNYELCDTYPTILVVPYKATEDDLRKVATFRSRC----RIPVMSWFHKENHAVITRCSQP--- 278

  Fly  1244 SVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSD 1308
             ::||    :|...          :.|:.:|.||......|.|.:.
Zfish   279 -LVGM----SGKRN----------KDDERYLDLIREANGTTKLTIY------------------- 309

  Fly  1309 DRQPLTPELSRKHKNNLDISDGNKSSQGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMN 1373
            |.:|           |:: :..||::.||..|                         ..|..|
Zfish   310 DARP-----------NVN-AVANKATGGGYEG-------------------------DDAYQN-- 335

  Fly  1374 VDFCADFIPVDYPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSL------ 1432
                |:.:.:|..:|...|.:.|||.....|:              ||:|.||..:.|.
Zfish   336 ----AELVFLDIHNIHVMRESLKKLKDIVYPN--------------VEESHWLSSLESTHWLEHI 382

  Fly  1433 -MQLSGA--VVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFG 1494
             :.||||  |.|.:. ..||||:...||.|.||||:|::.|.||.|||:|.||:||:||||::||
Zfish   383 KLVLSGAIQVADKVS-SGSSVMVHCSDGWDRTAQLTSLSMLMLDSYYRTLRGFQVLMEKEWISFG 446

  Fly  1495 HRFAHRSNLKPSHANTNIA---FAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFR 1556
            |:||.|.    .|.:.|.|   .:|.||||:|.|.|:.:|||.|||||:..|..:..|..||||.
Zfish   447 HKFASRI----GHGDKNHADQDRSPIFLQFIDCVWQMTKQFPTAFEFNERLLVVILDHLYSCRFG 507

  Fly  1557 TFLFDCELERSDSGIAAMEDKRGSLNAKHMFGAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIG 1621
            |||::||..|..:                                     ::|::..
Zfish   508 TFLYNCESVRDSN-------------------------------------NVRTKTV-------- 527

  Fly  1622 HSIFDYIERQHNKTPIFYNFLYSGDKSVTLRPQNNVAALDLWCYY 1666
             |::.||   ::.|.::.|..|:.:.|..|.|..::..|:||..|
Zfish   528 -SLWSYI---NSDTSLYINPFYTPESSRVLYPVASMRHLELWVTY 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:280329
		dDENN	384..452	CDD:129037
		SBF2	585..807	CDD:289132
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396	20/113 (18%)
		Myotub-related	1161..1565	CDD:284109	124/420 (30%)
		C1	1791..1838	CDD:237996
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
		PH	1891..1992	CDD:278594
mtm1	NP_001032773.2	PH-like	77..176	CDD:327399	25/130 (19%)
		Myotub-related	199..517	CDD:310891	128/454 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590774
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840