DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sbf and zgc:154055

DIOPT Version :9

Sequence 1:	NP_477401.2	Gene:	Sbf / 41427	FlyBaseID:	FBgn0025802	Length:	1993	Species:	Drosophila melanogaster
Sequence 2:	NP_001070610.1	Gene:	zgc:154055 / 556036	ZFINID:	ZDB-GENE-060929-612	Length:	567	Species:	Danio rerio

Alignment Length:	427	Identity:	106/427 - (24%)
Similarity:	174/427 - (40%)	Gaps:	105/427 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1148 LLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHL 1212
            |.:|:...:..||.    |.:          :|:|..|:.|:.|.|||:.::.|.:..|..::..
Zfish   138 LSSTEQYYKQTERL----WDK----------WRVSTVNSDYSVCPSYPSAVIVPREVDDDKLVRS 188

  Fly  1213 GRCFKGQRIPLPTW-RHANGALLIRGGQPNSKSVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLAL 1276
            .|..:|.|.|:.:: .|.|..:::|..||           .||:...      ...|.:....|:
Zfish   189 ARFRQGSRFPVLSYCHHRNRMVIMRSSQP-----------LTGANRK------RCREDELVLQAV 236

  Fly  1277 INTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELSRKHKNNLDISDGNKSSQGGKGGT 1341
            |:                    .|.||:.                   :|:    :|:|..:...
Zfish   237 ID--------------------GSEMGYI-------------------IDL----RSAQQAQQAR 258

  Fly  1342 MKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIPVDYPDIRQSRPAFKKLIRAC-MPS 1405
            |.|....|.:......|::...|:.:......:                      ||:.|| ..|
Zfish   259 MTGGGFESKSSYNNWKRIHRHHERGKVLQESLI----------------------KLVEACGDQS 301

  Fly  1406 HNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQL 1470
            |:.:.     :...:|.|.||..:.|.:..:|.|.:.::....||::...:|:|.|..:||:|||
Zfish   302 HSVDR-----WLSKLENSKWLSHVHSALSTAGLVAECVERDAHSVLVHGSEGTDNTLLVSSLAQL 361

  Fly  1471 CLDPYYRSLDGFRVLVEKEWLAFGHRFAHRS-NLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPM 1534
            .|||..|||.||..|:|::|:..||.|..|. :...|||... ...||||..||.|.|:.||||:
Zfish   362 ILDPASRSLSGFLCLLERDWIQAGHPFQLRCVHSAYSHARLK-QECPTFLLLLDCVWQVWRQFPL 425

  Fly  1535 AFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGI 1571
            |.||::..|..||....:..:.|||.:.|.||..:|:
Zfish   426 AMEFSEALLLRLAQDVYASDYGTFLCNSEQERYAAGV 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:280329
		dDENN	384..452	CDD:129037
		SBF2	585..807	CDD:289132
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396
		Myotub-related	1161..1565	CDD:284109	99/406 (24%)
		C1	1791..1838	CDD:237996
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
		PH	1891..1992	CDD:278594
zgc:154055	NP_001070610.1	PH-GRAM_MTMR9	1..109	CDD:275398
zgc:154055	NP_001070610.1	Myotub-related	120..456	CDD:284109	103/419 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590777
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840