Protein Alignment Sbf and mtmr1a

DIOPT Version :10

• Sequence 1: NP_477401.2
• Gene: Sbf / 41427
• FlyBaseID: FBgn0025802
• Length: 1993
• Species: Drosophila melanogaster
• Sequence 2: XP_073762672.1
• Gene: mtmr1a / 553750
• ZFINID: ZDB-GENE-050522-518
• Length: 699
• Species: Danio rerio
• Alignment Length: 805
• Identity: 184/805 - (22%)
• Similarity: 301/805 - (37%)
• Gaps: 225/805 - (27%)

  Fly   912 EAKRHPHVQKPKIQTPCLLPGEDLVTDHLRCFLMPDGREDETQCLIPAEGALFLTNYRVIFKGSP 976
            :.:.||...:..:..|......:|..:       |..|:|....|....|:
Zfish     4 QQQHHPSGSESPVLPPVARKPRNLGVN-------PASRQDSVDSLDSPTGS-------------- 47

  Fly   977 CDPLFCEQVIVRTF--------PIASLLKEKKISVLYLAHLDQTLTEGLQLRSSSFQLIKVAFDP 1033
             ...:|:|:|..|.        |..|:.:|.||.    ..:|..:::....||.........||.
Zfish    48 -HVEWCKQLIAATISSQITSGVPSESIHRESKIG----KKIDTRVSKRPNFRSQDSGEDGCQFDS 107

  Fly  1034 --EVTPEQIESFRKILSKARHPFDEFEYFAFQSYGTMLQGVAPLKTKEKYSTLKGFAKKTLLRGA 1096
              |:.....:.||.:...|  |.||......::..|.::.|..:      ....|....||....
Zfish   108 DCELPSHTSQVFRDVRRPA--PMDEVPLVPGETIKTTVKDVMYI------CPFTGAVTGTLTITD 164

  Fly  1097 KKAGFKQKQQTKRKLVSDYDYGSADAQETQSIDD--ELEDGDEFETQNNAMPRLLTTKD------ 1153
            .|..|...:: ....:.|.:.|:....||.|:..  |...|.|...::...||....|:
Zfish   165 YKLYFVSLER-DAPFILDVNLGAISRLETISVQSLGENTSGMEIVCKDMRSPRFAYKKEEQSKLE 228

  Fly  1154 -VERMRERSY---------------------------VQDWKRLGFDAESQRGFRISNANTSYAT 1190
             :|.:.:.::                           |.::||:|...||   :.||..|::|..
Zfish   229 ILETLTKYAFPLSNELSLFAFQYKEQFPEDGWKVYDPVAEYKRMGLPNES---WSISKINSNYEV 290

  Fly  1191 CRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRH-ANGALLIRGGQPNSKSVIGMLKNTTG 1254
            |.:|||::|.|....:..|..:.......|||:.:|.| ...|.::|..||           ..|
Zfish   291 CDTYPALLVTPTSIKEDEIRRVASFRVKHRIPVLSWIHPETQATIVRCSQP-----------MVG 344

  Fly  1255 STTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELSR 1319
            .|.....:..||                               :.::|..:            ::
Zfish   345 PTDRRCKEDEHY-------------------------------LQTIMDAN------------AQ 366

  Fly  1320 KHKNNLDISDGNKSSQGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIPVD 1384
            .||  |.|.|..:::......|..|..:|...:|                 ||.::|      ::
Zfish   367 SHK--LAIFDARQNTVAHNHKTKDGGYENENFYP-----------------NMELNF------LE 406

  Fly  1385 YPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAV--VDLIDLQE 1447
            .|:|...|.:.:||.....|:     .:.|.:...::.:.||:.|..|  |:|||  .|.::..:
Zfish   407 IPNIHVMRESLRKLKEVVYPT-----IEEQRWHSAIDATHWLEYIRLL--LAGAVRIADKVESSK 464

  Fly  1448 SSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHR-SNLKPSHANTN 1511
            |||::...||.|.||||:|::.|.||.|||:|.||:||:||||::|||:||.| .:...:|||:.
Zfish   465 SSVVVHCSDGWDRTAQLTSLSMLMLDSYYRTLRGFQVLLEKEWISFGHKFAARIGHGDENHANSE 529

  Fly  1512 IAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGIAAMED 1576
              .:|.|:||:|.|.|:.||||.|||||:.:|..:..:..||.|.|||::.|.||.:..:
Zfish   530 --RSPLFVQFIDCVWQMMRQFPSAFEFNELFLITILDYLYSCLFGTFLYNSEQERVEKEV----- 587

  Fly  1577 KRGSLNAKHMFGAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIGHSIFDYIERQHNKTPIFYNF 1641
                                                     ||...|::.||..|...   |.|.
Zfish   588 -----------------------------------------NRKTVSLWSYINSQSED---FTNP 608

  Fly  1642 LYSGDKSVTLRPQNNVAALDLWCYY 1666
            .|...::..|.|..::..|:||..|
Zfish   609 FYVDYENHVLYPLASLRHLELWVGY 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:460461
		dDENN	384..452	CDD:129037
		SBF2	584..807	CDD:463536
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396	23/123 (19%)
		PTP-MTMR5-like	1179..1531	CDD:350382	95/355 (27%)
		C1_Sbf-like	1790..1840	CDD:410377
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
mtmr1a	XP_073762672.1	None