Protein Alignment Sbf and mtmr3

DIOPT Version :10

• Sequence 1: NP_477401.2
• Gene: Sbf / 41427
• FlyBaseID: FBgn0025802
• Length: 1993
• Species: Drosophila melanogaster
• Sequence 2: XP_021333893.2
• Gene: mtmr3 / 393838
• ZFINID: ZDB-GENE-091204-465
• Length: 1186
• Species: Danio rerio
• Alignment Length: 873
• Identity: 214/873 - (24%)
• Similarity: 336/873 - (38%)
• Gaps: 254/873 - (29%)

  Fly   903 IESLEPVYLEAKRHPHVQKPKIQTPCLLPGEDLVTDHLRCFLMPDGREDETQCLIPAEGALF-LT 966
            :|.::...:..::.|.:::..:|.|                 .|:...:.|:.:..||.|:. ::
Zfish     9 LECIQANQIFPRKPPVLEEEDLQVP-----------------FPELHGEFTEYVGRAEDAVIAMS 56

  Fly   967 NYR--VIFKGSPCDPLFCEQVIVRTFPIASLLKEKKISVLYLAHLDQTLTEGLQLRSSSFQLIKV 1029
            :||  :.||.|..:...||..:    |: .|::..:...::..|          :.....::|:.
Zfish    57 SYRLHIKFKESVVNNCSCEVSV----PL-QLIECVECRDMFQLH----------ITCKDCKIIRC 106

  Fly  1030 AFDPEVTPEQIESFRKILSKARHP---FDEFEYFAFQSYGTMLQGVAPLKTKEKYSTLKGFAKKT 1091
            .|.   |.||.:.:.|.|:.|..|   .:|...|||.::      ...|.|.||.
Zfish   107 QFS---TFEQCQEWLKRLTAAVRPPSRIEELFSFAFHAW------CVDLYTGEKE---------- 152

  Fly  1092 LLRGAKKAGFKQKQQTKRKLVSDYDYGSADAQETQSIDDELEDGDEFETQNNAMPRLLTTKDVER 1156
                                                     :.||.....::.|.|.  ..:|||
Zfish   153 -----------------------------------------QHGDLCRPGDHVMSRF--HNEVER 174

  Fly  1157 MRERSYVQDWKRLGFDAESQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRI 1221
            |            |||  :|..:|:|..|..|..|.|||.:::.|...:|..:.::......:||
Zfish   175 M------------GFD--TQNAWRVSEINNKYKLCSSYPQLLLVPAWITDKELENVAAFRSWKRI 225

  Fly  1222 PLPTWRH-ANGALLIRGGQPNSKSVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTP 1285
            |...:|| :.||::.|.|||         :.:.....||  |..|          |:.::.:
Zfish   226 PAVVYRHQSTGAVIARCGQP---------EVSWWGWRNA--DDEH----------LVQSIAR--- 266

  Fly  1286 LALNQYSGMNLSMSSLMGHSSSDDRQPLTPELSRKHKNNLDISDGNKSSQGGKGGTMKGNPKNSL 1350
                   ...:..||..|.|:.        .|||::.|..|:||.:..|     .....:...:|
Zfish   267 -------ACAVDSSSCKGVSNG--------SLSREYTNGADLSDVDFES-----SMTNSSEVETL 311

  Fly  1351 AHPFRKM-----RLYALGEKSQAKSNMNVDFCADFIP------VDYPDIRQSRPAFKKLIRACMP 1404
            |...||:     |.||....::||.....  |.::.|      :...:|...|.:|:.|...|
Zfish   312 AIQPRKLLILDARSYAAAVANRAKGGGCE--CPEYYPNCEVVFMGMANIHSIRKSFQSLRFLC-- 372

  Fly  1405 SHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQ 1469
               |...|..::...:|.:.|||.:|.|::.|..|.:.:|.....|::...||.|.|.|:.::|:
Zfish   373 ---TQMPDPANWLSALESTKWLQHLSLLLKASLLVSNAVDRDHRPVLVHCSDGWDRTPQIVALAK 434

  Fly  1470 LCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPM 1534
            |.||||||:::||:||||.|||.|||:||.|.....:..:.| ...|.|||:||.|||||||||.
Zfish   435 LLLDPYYRTIEGFQVLVETEWLDFGHKFADRCGHGENAEDLN-ERCPVFLQWLDCVHQLQRQFPC 498

  Fly  1535 AFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGIAAMEDKRGSLNAKHMFGAGGMATNGSDD 1599
            :||||:.:|..|..|:.||.|.|||.:...||.|..|                         .:.
Zfish   499 SFEFNEAFLVKLVQHTYSCLFGTFLCNSGKEREDRRI-------------------------QER 538

  Fly  1600 ECSVYPLDIRSQRAPAPLNRIGHSIFDYIERQHNKTPIFYNFLYSGDKSVTLRPQNNVAALDLW- 1663
            .|||:.|...:.|:                        |.|.|||......|.|..:|..|.||
Zfish   539 TCSVWSLLRAANRS------------------------FGNMLYSSHSETVLHPVCHVRNLMLWT 579

  Fly  1664 CYY------TNEELAQGAPYDLEVTTVDDEIDLSETKGKRMVITAGYDNMEKCNPSAYVC----- 1717
            ..|      |.......|||.......:|     :..|:|.. |..:||:    |||  |
Zfish   580 AVYLPSSSPTTPSDDSCAPYPAPGANPED-----QPLGRRPK-TRSFDNL----PSA--CEVGNP 632

  Fly  1718 LLSEVKQAETERGHLPQKWLQVWNSLEV 1745
            |.|..:.::..   |.:||.....|||:
Zfish   633 LTSNRRSSDPS---LNEKWQDHRRSLEL 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:460461
		dDENN	384..452	CDD:129037
		SBF2	584..807	CDD:463536
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396	21/116 (18%)
		PTP-MTMR5-like	1179..1531	CDD:350382	106/363 (29%)
		C1_Sbf-like	1790..1840	CDD:410377
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
mtmr3	XP_021333893.2	None