DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sbf and Mtmr9

DIOPT Version :9

Sequence 1:	NP_477401.2	Gene:	Sbf / 41427	FlyBaseID:	FBgn0025802	Length:	1993	Species:	Drosophila melanogaster
Sequence 2:	NP_001005761.1	Gene:	Mtmr9 / 282584	RGDID:	628840	Length:	549	Species:	Rattus norvegicus

Alignment Length:	444	Identity:	111/444 - (25%)
Similarity:	176/444 - (39%)	Gaps:	127/444 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1132 LEDG-------DEFETQNNAMPRLLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISNANTSYA 1189
            :|||       .|||..::|                  ..:|             |:|..|..::
  Rat   120 IEDGWHSFLPEQEFEFYSSA------------------TSEW-------------RLSYVNKEFS 153

  Fly  1190 TCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRH-ANGALLIRGGQPNSKSVIGMLKNTT 1253
            .|.:||..::.|....|.|:..:.....|.|.|:.::.| .||.:::|.|||        |..|.
  Rat   154 ICPTYPPTVIVPKSIDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQP--------LTGTN 210

  Fly  1254 GSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELS 1318
            |....         |.:|    |||...:                                   :
  Rat   211 GRRCK---------EDEK----LINATLR-----------------------------------A 227

  Fly  1319 RKHKNNLDISDGNKSSQG-GKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIP 1382
            .|....:|....|.:.|. .|||..:..     ||..:..|::...|:
  Rat   228 GKRGYLIDTRSLNVAQQARAKGGGFEQE-----AHYPQWRRIHKSIER----------------- 270

  Fly  1383 VDYPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQE 1447
              |..:::|   ..||:.||  :..|:..|  .:...:|.|:||..|..::..:......||.:.
  Rat   271 --YHVLQES---LIKLVEAC--NEQTHSMD--RWLGKLEASNWLTHIKEILTTACLAAQCIDREG 326

  Fly  1448 SSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTNI 1512
            :||::...:|:|.|.|::|:||:.|:|..|::.||..|:|:|||..||.|..|.......::...
  Rat   327 ASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSSKQK 391

  Fly  1513 AFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELER 1566
            ..||.||.|||.|.|:.||||.:||||:.:|..|..|:.:.:|.|||.:.|.||
  Rat   392 WEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNSENER 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:280329
		dDENN	384..452	CDD:129037
		SBF2	585..807	CDD:289132
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396
		Myotub-related	1161..1565	CDD:284109	102/405 (25%)
		C1	1791..1838	CDD:237996
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
		PH	1891..1992	CDD:278594
Mtmr9	NP_001005761.1	PH-GRAM_MTMR9	1..97	CDD:275398
Mtmr9	NP_001005761.1	Myotub-related	121..446	CDD:399535	111/443 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840