DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sbf and Mtmr9

DIOPT Version :9

Sequence 1:NP_477401.2 Gene:Sbf / 41427 FlyBaseID:FBgn0025802 Length:1993 Species:Drosophila melanogaster
Sequence 2:NP_808262.1 Gene:Mtmr9 / 210376 MGIID:2442842 Length:545 Species:Mus musculus


Alignment Length:445 Identity:113/445 - (25%)
Similarity:177/445 - (39%) Gaps:129/445 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly  1132 LEDG-------DEFETQNNAMPRLLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISNANTSYA 1189
            :|||       .|||..::|                  ..:|             |:|..|..::
Mouse   120 IEDGWHSFLPEQEFEFYSSA------------------TSEW-------------RLSYINKDFS 153

  Fly  1190 TCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRH-ANGALLIRGGQPNSKSVIGMLKNTT 1253
            .|.|||..::.|....|.|:..:.....|.|.|:.::.| .||.:::|.|||        |..|.
Mouse   154 ICPSYPPTVIVPKSVDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQP--------LTGTN 210

  Fly  1254 GSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELS 1318
            |....         |.:|    |||...:                                   :
Mouse   211 GRRCK---------EDEK----LINATLR-----------------------------------A 227

  Fly  1319 RKHKNNLDISDGNKSSQG-GKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIP 1382
            .|....:|....|.:.|. .|||..:..     ||..:..|::...|:                 
Mouse   228 GKRGYLIDTRSLNVAQQARAKGGGFEQE-----AHYPQWRRIHKSIER----------------- 270

  Fly  1383 VDYPDIRQSRPAFKKLIRAC-MPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQ 1446
              |..:::|   ..||:.|| ..:||.:...|:     :|.|:||..|..::..:......||.:
Mouse   271 --YHVLQES---LIKLVEACNEQTHNMDRWLGK-----LEASNWLTHIKEILTTACLAAQCIDRE 325

  Fly  1447 ESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTN 1511
            .:||::...:|:|.|.|::|:||:.|:|..|::.||..|:|:|||..||.|..|.......::..
Mouse   326 GASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSSKQ 390

  Fly  1512 IAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELER 1566
            ...||.||.|||.|.|:.||||.:||||:.:|..|..|:.:.:|.|||.:.|.||
Mouse   391 KWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNNESER 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SbfNP_477401.2 uDENN 1..91 CDD:214824
DENN 142..325 CDD:280329
dDENN 384..452 CDD:129037
SBF2 585..807 CDD:289132
PH-GRAM_MTMR5_MTMR13 933..1047 CDD:275396
Myotub-related 1161..1565 CDD:284109 104/406 (26%)
C1 1791..1838 CDD:237996
PH_Sbf1_hMTMR5 1888..1993 CDD:269941
PH 1891..1992 CDD:278594
Mtmr9NP_808262.1 PH-GRAM_MTMR9 1..97 CDD:275398
Myotub-related 108..444 CDD:284109 111/442 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167846047
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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