DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sbf and XB5960519

DIOPT Version :9

Sequence 1:	NP_477401.2	Gene:	Sbf / 41427	FlyBaseID:	FBgn0025802	Length:	1993	Species:	Drosophila melanogaster
Sequence 2:	XP_031751608.1	Gene:	XB5960519 / 100216114	XenbaseID:	XB-GENE-5960520	Length:	563	Species:	Xenopus tropicalis

Alignment Length:	517	Identity:	127/517 - (24%)
Similarity:	191/517 - (36%)	Gaps:	172/517 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1160 RSYVQDWKRLGFDAESQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLP 1224
            |:...||             |:|..|..:..|.||||.::.|..|||..:.......:..|.|:.
Frog   161 RAETDDW-------------RLSEVNLDFKICPSYPAKVIVPRICSDETLQKAAAFRQAGRFPVL 212

  Fly  1225 TWRH-ANGALLIRGGQPNSKSVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLAL 1288
            ::.| ||...|:|..||    :.|         |..||        .|:..||:|
Frog   213 SYYHSANQTALLRSAQP----LFG---------TAPHH--------CKHDEALLN---------- 246

  Fly  1289 NQYSGMNLSMSSLMGHSSS---DDRQPLTPELSRKHKNNLDISDGNKSSQGGKGGTMKGNPKN-- 1348
                      ::||..||.   |.|.....:.:|              ::|| |...|...:|
Frog   247 ----------AALMEQSSGFIIDTRSAQEAKQAR--------------NEGG-GTESKSRYRNWR 286

  Fly  1349 SLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIPVDYPDIRQSRPAFKKLIRACMPSHNTNEADG 1413
            .|..|..:      |...|......|..|.|      |.|..:|
Frog   287 VLHRPLER------GHALQDSLVRLVVTCYD------PSIGMTR--------------------- 318

  Fly  1414 QSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRS 1478
              :...::.:.||..:...:..:|.:.:.|:.:.::|::..|||:|.|..|:|:|||.|.|..|:
Frog   319 --WLSKLQAARWLSHVKEALSTAGLIAECIERECANVLVHGEDGTDNTLLLTSLAQLILCPESRT 381

  Fly  1479 LDGFRVLVEKEWLAFGHRFAHR---SNLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFND 1540
            :|||:.|:|:|||..||.|..|   |....|.|...   :|.||.|||...||.||||.|.|||:
Frog   382 MDGFQDLIEREWLQAGHPFQLRCAQSGWSQSRAQQE---SPHFLLFLDCCWQLGRQFPRALEFNE 443

  Fly  1541 FYLRFLAYHSVSCRFRTFLFDCELERSDSGIAAMEDKRGSLNAKHMFGAGGMATNGSDDECSVYP 1605
            .:|..||.|:.|..:.:||.:.|.||                                  |. |.
Frog   444 RFLCTLATHAYSSEYGSFLCNNEKER----------------------------------CQ-YE 473

  Fly  1606 LDIRSQRAPAPLNRIGHSIFDYI----ERQHNKTPIFYNFLYSGDKSVTLRPQNNVAALDLW 1663
            :..|:           ||::.::    |||....||:.      :..:.:.|.....:|.||
Frog   474 VQDRT-----------HSLWGHLNQPKERQQLLNPIYQ------ENPLVIWPSVAPQSLQLW 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:280329
		dDENN	384..452	CDD:129037
		SBF2	585..807	CDD:289132
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396
		Myotub-related	1161..1565	CDD:284109	110/412 (27%)
		C1	1791..1838	CDD:237996
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
		PH	1891..1992	CDD:278594
XB5960519	XP_031751608.1	PH-GRAM_MTMR9	1..121	CDD:275398
XB5960519	XP_031751608.1	Myotub-related	147..470	CDD:399535	113/449 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910