Protein Alignment Sbf and mtmr4

DIOPT Version :10

• Sequence 1: NP_477401.2
• Gene: Sbf / 41427
• FlyBaseID: FBgn0025802
• Length: 1993
• Species: Drosophila melanogaster
• Sequence 2: XP_004911826.1
• Gene: mtmr4 / 100151726
• XenbaseID: XB-GENE-986315
• Length: 1093
• Species: Xenopus tropicalis
• Alignment Length: 962
• Identity: 220/962 - (22%)
• Similarity: 342/962 - (35%)
• Gaps: 327/962 - (33%)

  Fly   907 EPVYLEAKRHPHVQKPKIQTPCLLPGEDLVTDHLRCFLMPDGREDETQC---LIPAEGALFL--- 965
            ||..||          .||...|.|..:||.:           |::.|.   ::|.||..:|
 Frog    19 EPPSLE----------YIQAKDLFPPRELVKE-----------EEKLQVPFPVLPGEGVEYLGSA 62

  Fly   966 -------TNYRVIFKGSPCDPLFCEQVIVRTFPIASLLKEKKISVLYLAHLDQTLTEGLQLRSSS 1023
                   :|||:..|       |.:.||                     ::...:.|.::.| ..
 Frog    63 NDAVIAISNYRLHIK-------FKDSVI---------------------NVPLRMIEAVESR-DM 98

  Fly  1024 FQLIKVAFDPEV------TPEQIESFRKILSKAR-HPFDEFEYFAFQSYGTMLQGVAPLKTKEKY 1081
            |||..:..|.:|      |.:|.:.:.|.||:|. .|..:.:.||| :|....||:..
 Frog    99 FQLQIICKDSKVVRCHFSTFKQCQEWLKRLSRATLRPAKQEDLFAF-AYHAWCQGICT------- 155

  Fly  1082 STLKGFAKKTLLRGAKKAGFKQKQQTKRKLVSDYDYGSADAQETQSIDDELEDGDEFETQNNAMP 1146
                                                                  ||.|      |
 Frog   156 ------------------------------------------------------DEEE------P 160

  Fly  1147 RLLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMH 1211
            .:...:..:.::.| :..:..|:|||.  |..:|:|..|.:|..|.|||..::.||..:|..:.:
 Frog   161 LIHLCRPGDHVKSR-FQMELVRMGFDL--QNAWRVSEINNNYKLCPSYPQKLLVPVWITDKELEN 222

  Fly  1212 LGRCFKGQRIPLPTWRHA-NGALLIRGGQPNSKSVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLA 1275
            :......:|||:..:||. .||::.|..||         :.:.....||         .|:|.:.
 Frog   223 VASFRSWKRIPVVVYRHTRTGAVIARCSQP---------EISWWGWRNA---------DDEYLVT 269

  Fly  1276 LINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELSRKHKNNLDISDGNKSS------ 1334
            .|.....|.|..                      |.|.....|:::|:..|.||.:..|
 Frog   270 SIAKACALNPAV----------------------RMPNGNASSKENKDGSDNSDTDFDSSLTACP 312

  Fly  1335 -QGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIP------VDYPDIRQSR 1392
             :||      |.|:..|   ....|.|.....::||.....  |.::.|      :...:|...|
 Frog   313 VEGG------GVPQKLL---IVDARSYTAAVANRAKGGGCE--CEEYYPNCEVAFMGMANIHSIR 366

  Fly  1393 PAFKKLIRACMPSHNTNEA-DGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLED 1456
            .:|:.|...|      |:. |..::...:|.:.|||.:|::::.:..|.:.:|.:|..|::...|
 Frog   367 NSFQYLRAVC------NQVPDPGNWLSALESTKWLQHLSAMLKAATVVANAVDREERPVLVHCSD 425

  Fly  1457 GSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFA----HRSNLKPSHANTNIAFAPT 1517
            |.|.|.|:.|:|:|.||||||:|:||:||||.:||.:||:||    |:.|.:..:..     .|.
 Frog   426 GWDRTPQIVSLAKLLLDPYYRTLEGFQVLVETDWLDYGHKFADRCGHQENTEDQNEQ-----CPV 485

  Fly  1518 FLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGIAAMEDKRGSLN 1582
            |||:||.:|||..|||..||||..:|..|..|:.||.:.|||.:...||....|.    ||
 Frog   486 FLQWLDCIHQLLLQFPCHFEFNHAFLVKLVQHTYSCLYGTFLANNLCEREMRNIY----KR---- 542

  Fly  1583 AKHMFGAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIGHSIFDYIERQHNKTPIFYNFLYSGDK 1647
                             .|||:.|                      .|..||.  |:|.||....
 Frog   543 -----------------TCSVWSL----------------------LRTGNKN--FHNLLYMPGS 566

  Fly  1648 SVTLRPQNNVAALDLWCYYTNEELAQGAPYDLEVTTVDDEIDLSETKGK-----------RMVIT 1701
            .:.|.|..:|.||.||       .|...|.....|.:||.:::..|...           |:..|
 Frog   567 DLVLHPVCHVRALQLW-------TAVYLPATSPCTPMDDRMEMYLTPASQGPEFNARSLDRLPKT 624

  Fly  1702 AGYDN-------------------------MEKCNPSAYVCLLSEVKQA-ETERGHLPQKWLQVW 1740
            ...||                         :|.|:.|         |:. |||...:.|:.|...
 Frog   625 RSMDNLLTACDGGGLLTRTSSDPNLNHQGILEPCSSS---------KEGNETEIHDIQQQALSTE 680

  Fly  1741 NSLEVPQLEPVA---RNTSLGNIFVQTHQHKRSTLEIIMKGRLAGYQDKYFH 1789
            ...|...|:..:   .|...|....||:..:.:....:...:|....|:..|
 Frog   681 PKEEGRDLDSKSTECENKDTGEFRNQTNNEQNALKNSLSVAKLDSVDDRRDH 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:460461
		dDENN	384..452	CDD:129037
		SBF2	584..807	CDD:463536
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396	25/132 (19%)
		PTP-MTMR5-like	1179..1531	CDD:350382	101/370 (27%)
		C1_Sbf-like	1790..1840	CDD:410377	220/962 (23%)
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941
mtmr4	XP_004911826.1	PH-GRAM_MTMR4	37..150	CDD:270150	33/153 (22%)
		PTP-MTMR4	188..495	CDD:350435	98/368 (27%)
		FYVE_MTMR4	1009..1068	CDD:277272