Protein Alignment HisCl1 and Gabrp

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_112291.1
• Gene: Gabrp / 81658
• RGDID: 620532
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 461
• Identity: 135/461 - (29%)
• Similarity: 216/461 - (46%)
• Gaps: 66/461 - (14%)

  Fly     6 SKLVEFRCLIALAIYLHALEQSIQHCHCVHGYRNNTESAELVSHYESSLSLPDILPIPSKTYDKN 70
            |..:.|.||..||..:           |:.|.:.|.|.:.     ...||||....: :..|:|.
  Rat     4 SLYLAFVCLNLLAQRM-----------CIQGNQFNVEVSR-----SDKLSLPGFENL-TAGYNKF 51

  Fly    71 RAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLH 135
            ..|...|.|..:...:.:.|:.||:|.:|.|...|:|.|.|.||||....|.|   ..||...:.
  Rat    52 LRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFEGNKS---FTLDARLVE 113

  Fly   136 SIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMI 200
            .:|.||.:...:||...||:::.|..:.|:.:.|:||..::|..::|.|....||.|||.|.:.:
  Rat   114 FLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQL 178

  Fly   201 ESLSHTVEDLVFIWNMTDPLVVNTE-IELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLG 264
            ||..:...|:.|.|...:..|...| :.|.|..|...:|.....:..|||:|.|.:.|.|||.:.
  Rat   179 ESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQYFTLVTVSQQETGNYTRLVLQFELRRNVL 243

  Fly   265 YHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVS-YVKAIDV 328
            |.:..||:||..:||:||:||||..|::|||..:|||::|::.|....|:.|||..: ::|||||
  Rat   244 YFILETYVPSTFLVVLSWVSFWISLESVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDV 308

  Fly   329 WMSSCSVFVFLSLMEFAV--------------------------------VNNFMGPVATKAMK- 360
            ::..|..|||.:|:|:||                                :::|...::..:::
  Rat   309 YLGICFSFVFGALLEYAVAHYSSLQQMAVKDRGPAKDSEEVNITNIINSSISSFKRKISFASIEI 373

  Fly   361 -----GYSDENISDLDDLKSALQHHRESIIEPQYDTFCHGHATAIYIDKFSRFFFPFSFFILNIV 420
                 .|||..:...|..|...:.....||:  |.|.    .....:|::|:..||..|.:.|:.
  Rat   374 SGDNVNYSDLTMKASDKFKFVFREKIGRIID--YFTI----QNPSNVDRYSKLLFPLIFMLANVF 432

  Fly   421 YWTTFL 426
            ||..::
  Rat   433 YWAYYM 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	63/195 (32%)
		Neur_chan_memb	270..>350	CDD:280999	38/112 (34%)
Gabrp	NP_112291.1	LIC	43..437	CDD:273305	121/403 (30%)
		LGIC_ECD	60..241	CDD:355788	59/183 (32%)
		Cys-loop	159..174	CDD:349787	7/14 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810