Protein Alignment HisCl1 and gabra5

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_005166139.1
• Gene: gabra5 / 799124
• ZFINID: ZDB-GENE-081104-30
• Length: 453
• Species: Danio rerio
• Alignment Length: 398
• Identity: 125/398 - (31%)
• Similarity: 192/398 - (48%)
• Gaps: 52/398 - (13%)

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRL--RLPENMSEQYRIL 129
            ||....|.|..:.|.:..::.|.|...:::..|.|..|:|..|||:|.||  :.|..|.....:|
Zfish    60 YDNRLRPGLGEKVTEIKTNIFVTSFGPVSDTEMEYTIDVFFRQSWKDERLCFKGPMEMLPLNNLL 124

  Fly   130 DVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQ 194
                ..:||.||.||.|.||...|.|:.||..|.|..|.||||..:||:...|.|:.|.:|.|..
Zfish   125 ----ASNIWTPDTFFLNGKKSIAHNMTTPNKLLRLKDDGTLLYTMRLTISAECPMQLEDFPMDAH 185

  Fly   195 ICSMMIESLSHTVEDLVFIWNM---TDPLVVNTEIELPQLDISNNYTTDCTIEYSTGNFTCLAIV 256
            .|.:...|.::.:.::|:.|..   ...:|......|.|..:..:......|..|.|.:|.:...
Zfish   186 ACPLKFGSYAYPISEVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHTAGTEDISTSRGQYTVMMAH 250

  Fly   257 FNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVS 321
            |.|:|::||.:..||:|..:.|::|.:|||:..|::|||...|||::||:.|.:..::.|||.|:
Zfish   251 FYLKRKIGYFVIQTYMPCFMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 315

  Fly   322 YVKAIDVWMSSCSVFVFLSLMEFAVVNNF--------------------MGPVA-TKAMKGYS-- 363
            |..|:|.:::.|..|||.:|:|||.||.|                    ..|:| :|....::
Zfish   316 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWDGKKALEAQQPKKKDPLALSKKPNNFTAN 380

  Fly   364 ---DENISDLDD-----LKSALQHHRESIIEPQ--YDTFCHGHATAIYIDKFSRFFFPFSFFILN 418
               |..||.:.:     ||||   ..:...:|:  |::...       |||.||..||..|...|
Zfish   381 INKDAAISTISNSTTVQLKSA---EAKPAPDPKKTYNSVSK-------IDKMSRIVFPVLFGTFN 435

  Fly   419 IVYWTTFL 426
            :|||.|:|
Zfish   436 LVYWATYL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	60/199 (30%)
		Neur_chan_memb	270..>350	CDD:280999	35/79 (44%)
gabra5	XP_005166139.1	Neur_chan_LBD	19..442	CDD:332142	123/395 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900