Protein Alignment HisCl1 and gabrr2a

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_017207163.1
• Gene: gabrr2a / 751659
• ZFINID: ZDB-GENE-060825-164
• Length: 475
• Species: Danio rerio
• Alignment Length: 481
• Identity: 148/481 - (30%)
• Similarity: 224/481 - (46%)
• Gaps: 79/481 - (16%)

  Fly    12 RCLIALAIYLHALEQSIQHCHCVHGYRNN--TESAELVSHYESSLSLPDILPIPSKT-------- 66
            |.|:.|.::|    .|...|...|..|..  |.:.|...|..|....|   |..:|:
Zfish     6 RQLLILVLFL----GSFGECRNKHATRERRWTGAVETQKHGTSLAKKP---PDVTKSRRLKTEQL 63

  Fly    67 -----YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQY 126
                 :|....|...|....|...|.|.|||||:|..|.:...::|...|:|.||....:.::.
Zfish    64 LKVDDHDFTMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFTSSTNKS- 127

  Fly   127 RILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPH 191
            ...|...:..||.||.||.::|:...|:.:..|..|.::.|..:||..::|:..:|.|.|..:|.
Zfish   128 MTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTENIMLRVFPDGHVLYSLRVTVTAACNMDFSRFPL 192

  Fly   192 DTQICSMMIESLSHTVEDLVFIW-NMTDPLVVNTEIELPQLDISNNYTTDCTIEY-STGNFTCLA 254
            |:|.||:.:||.::|.|||:..| |..:.|.::.:|.|.|..|...:||.....| |||.:..|.
Zfish   193 DSQTCSLELESYAYTDEDLMLYWKNGDESLSIDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLY 257

  Fly   255 IVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPP 319
            |.|.|||.:.:.|..||.|:.|:|::||:||||...|:||||:||:|::||::|..|....|:|.
Zfish   258 INFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVNASMPR 322

  Fly   320 VSYVKAIDVWMSSCSVFVFLSLMEFAVVNNF--------------------------MGPVATKA 358
            |||:||:|:::....||||||::|:|.||..                          |....|..
Zfish   323 VSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERRERKLRDRAVREQSLPCTCGMSHTRTMM 387

  Fly   359 MKG-YSDENISDLDDLKSALQHHRESIIEPQYDTFCH-----------------------GHATA 399
            :.| ||:.:.:.|.....|...|.|.:.|.|.....|                       .||
Zfish   388 LDGTYSEADTNSLAGYTEAPMVHEEVVPEKQEHMVVHLSVSSESTNTKKKGIRALRIMQNTHA-- 450

  Fly   400 IYIDKFSRFFFPFSFFILNIVYWTTF 425
              |||:||..||.::.|.|::||:.:
Zfish   451 --IDKYSRMIFPGAYIIFNLIYWSVY 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	65/196 (33%)
		Neur_chan_memb	270..>350	CDD:280999	41/79 (52%)
gabrr2a	XP_017207163.1	LIC	43..474	CDD:273305	137/438 (31%)
		Neur_chan_LBD	60..266	CDD:280998	66/206 (32%)
		Neur_chan_memb	273..471	CDD:280999	64/201 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810