Protein Alignment HisCl1 and gabrp

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_005173350.1
• Gene: gabrp / 566633
• ZFINID: ZDB-GENE-081028-62
• Length: 464
• Species: Danio rerio
• Alignment Length: 466
• Identity: 132/466 - (28%)
• Similarity: 219/466 - (46%)
• Gaps: 70/466 - (15%)

  Fly    21 LHALEQSIQHCHCV------------------HGYRNNTESAELVSHYESSLSLPDILPIPSKTY 67
            ||:.:.|..|.|.:                  .|:..|.     ...:..|...|.|..: .|.|
Zfish     7 LHSYQSSGLHYHRMLLNLLFWTSLFLLITNGERGFYGNQ-----YGEWNDSQLQPTIQKL-MKGY 65

  Fly    68 DKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVD 132
            ::...|.....|..:...:.:.|:|:|:|.:|.|...|||.|.|||.||..|.|.|..   ||..
Zfish    66 NRYLRPNFNEGPVEIGMSLDIASIDAISEINMDYTATIFLRQRWRDSRLIFPGNESLS---LDGR 127

  Fly   133 WLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICS 197
            .:..:|.||.|..::|:...|::::.|..:.::.:.|:||..::|..::|.|....||.|.|.|:
Zfish   128 LVSLLWIPDTFIPDSKRSFLHDVTVENRLIRIFSNGTVLYALRITATIACNMDLTKYPMDRQECT 192

  Fly   198 MMIESLSHTVEDLVFIWNMTDPLVVNTE-IELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRR 261
            :.:||..:.:||:||.|...:..|...: :.|.|..:.:.||:.....|.||.:..|.:.|.|||
Zfish   193 LQLESWGYNLEDVVFYWTRGNDSVKGLDTLRLAQYSVESYYTSVTKAVYETGLYPKLILHFALRR 257

  Fly   262 RLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVS-YVKA 325
            .:.:.:..||:||.|:||:||:||||...::|||..:|||::||:.|....::.|||..: ::||
Zfish   258 NVLFFILETYVPSTLLVVLSWVSFWISQSSVPARTCIGVTTVLTMTTLMMGARTSLPNANCFIKA 322

  Fly   326 IDVWMSSCSVFVFLSLMEFA------VVNNFMGPVATKAMKGYSDEN-----ISDLDDLK----- 374
            |||::..|..|:|.:|:|:|      :.:..:..|..:.:|.:.:.|     :|.:...|
Zfish   323 IDVYLGICFTFIFGALLEYACAHFCTMQHQTIIDVQRELLKEFEESNGTTHLVSSMSPRKMKTED 387

  Fly   375 SALQHHRE--------SIIEPQYDTFCHGHATAIY----------------IDKFSRFFFPFSFF 415
            |..|...|        ..||...:..| |..|...                ||:.:|..||.:|.
Zfish   388 STKQEKPEQTVTCEENEAIEQTKEKGC-GLTTVKQMSRRAASMMSVENPHNIDRHARILFPMAFL 451

  Fly   416 ILNIVYWTTFL 426
            ::||.||..:|
Zfish   452 LINIFYWLYYL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	60/195 (31%)
		Neur_chan_memb	270..>350	CDD:280999	36/86 (42%)
gabrp	XP_005173350.1	Neur_chan_LBD	21..461	CDD:332142	126/449 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810