Protein Alignment HisCl1 and gabra4

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001017822.1
• Gene: gabra4 / 550520
• ZFINID: ZDB-GENE-050417-360
• Length: 557
• Species: Danio rerio
• Alignment Length: 493
• Identity: 121/493 - (24%)
• Similarity: 195/493 - (39%)
• Gaps: 137/493 - (27%)

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDV 131
            ||....|...|..|.|...:.|.|...:::..|.|..|:|..|:|.|.|||. |...|..|:.::
Zfish    59 YDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWVDRRLRY-EGPVEILRLNNL 122

  Fly   132 DWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQIC 196
             .:..:|.||.||:|.|:...|.|:.||....:..:.|:||..:||:...|.|:..::|.|...|
Zfish   123 -MVTKVWTPDTFFRNGKRSVAHNMTAPNRLFRIMKNGTILYTMRLTISAECPMRLVNFPMDGHSC 186

  Fly   197 SMMIESLSHTVEDLVFIWNMTDPLVVNTEIE---LPQLDISNNYTTDCTIEYSTGNFTCLAIVFN 258
            .:...|.::...::::.|.......|....|   |.|.|:.....:..|::..||.:..:.:.|:
Zfish   187 PLKFGSYAYPKTEMIYTWTKGPQHSVEVPPESSSLVQYDLIGQTVSSETVKSITGEYVVMTVYFH 251

  Fly   259 LRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYV 323
            |:|::||.:..||||..:.|::|.:||||..|::|||...|:|::||:.|.:..::.|||.|||.
Zfish   252 LKRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA 316

  Fly   324 KAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMKGYS------------------------- 363
            .|:|.:::.|..|||.:|:|||.||.|....|.:|.:..:
Zfish   317 TAMDWFIAVCFAFVFSALIEFAAVNYFTNAQAERAKRKQAKAAAAASVKSSTGKNKDTEEVLQQN 381

  Fly   364 -----------DENISDLDDLK------------------------------------------- 374
                       :.||....:.|
Zfish   382 SDTNGNLRKRVNSNIQPQAESKKTQRTEASSKSGASSSKPTLTSQSSSTSEGTSSFSSQSRLSPS 446

  Fly   375 ----------------------------------------SALQHH-----------RESIIEPQ 388
                                                    ||..||           :|:..:||
Zfish   447 SASQSNAAASSSSASKTTPPAPPSTPTVPDKPSPGTTPAGSAPLHHLLGPKLENIKKKEAKAQPQ 511

  Fly   389 YDTFCHGHATAIYIDKFSRFFFPFSFFILNIVYWTTFL 426
            ......|.|:.  ||:::|..||.||...|:|||..:|
Zfish   512 PAAPATGGASK--IDEYARILFPVSFGAFNMVYWVVYL 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	54/197 (27%)
		Neur_chan_memb	270..>350	CDD:280999	37/79 (47%)
gabra4	NP_001017822.1	Neur_chan_LBD	49..256	CDD:280998	55/198 (28%)
		Neur_chan_memb	263..543	CDD:280999	61/281 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810