Protein Alignment HisCl1 and nAChRbeta1

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 355
• Identity: 75/355 - (21%)
• Similarity: 134/355 - (37%)
• Gaps: 90/355 - (25%)

  Fly    67 YDKNRAP-KLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPR-------------LR 117
            |:|...| :.:.|...|.|.:..:.|.::||::....::::|...|.|.:             ||
  Fly    39 YNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQIMKSNVWLRLVWYDYQLQWDEADYGGIGVLR 103

  Fly   118 LPENMSEQYRILDVDWLHSIWRPD-CFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVL- 180
            ||.:              .:|:|| ..|.||          ..:|...|....|:|.:...|.:
  Fly   104 LPPD--------------KVWKPDIVLFNNA----------DGNYEVRYKSNVLIYPTGEVLWVP 144

  Fly   181 ------SCAMKFESYPHDTQICSMMIESLSHTVE-------------DLVFIWNMTDPLVVNTEI 226
                  ||.:....:|.|.|.|.|...|.:...:             ||...|......::....
  Fly   145 PAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNFVDLSDYWKSGTWDIIEVPA 209

  Fly   227 ELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEA 291
            .|...:..:|:.|:          |.:.....:||:..::..:..:|:.||..:..:.|::..||
  Fly   210 YLNVYEGDSNHPTE----------TDITFYIIIRRKTLFYTVNLILPTVLISFLCVLVFYLPAEA 264

  Fly   292 IPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLS-----LMEFAVVN-NF 350
             ..:||||::.||:|........:.|||.|.|..:   ::...:|.|:.     |:...::| ||
  Fly   265 -GEKVTLGISILLSLVVFLLLVSKILPPTSLVLPL---IAKYLLFTFIMNTVSILVTVIIINWNF 325

  Fly   351 MGPVATKAMKGYSDENISDLDDLKSALQHH 380
            .|| .|..|..|          ::|...|:
  Fly   326 RGP-RTHRMPMY----------IRSIFLHY 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	43/229 (19%)
		Neur_chan_memb	270..>350	CDD:280999	22/85 (26%)
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:273305	75/355 (21%)
		Neur_chan_LBD	28..236	CDD:280998	44/230 (19%)
		Neur_chan_memb	243..498	CDD:280999	31/117 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100