Protein Alignment HisCl1 and lgc-38

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001355511.1
• Gene: lgc-38 / 3565717
• WormBaseID: WBGene00017389
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 430
• Identity: 131/430 - (30%)
• Similarity: 207/430 - (48%)
• Gaps: 83/430 - (19%)

  Fly    66 TYDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILD 130
            ::|:...|...|.|..|.....|.::.:::|.||.|..|::|.|.|:||||....::.:...| .
 Worm    62 SHDRRIRPNYGGPPIEVNITAHVTTISAVSEVSMDYTLDLYLRQIWKDPRLAWESDVEDSLTI-G 125

  Fly   131 VDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQI 195
            :|.:.:||.||.||.|.||..|||.:..|.:|.:.:...:|...:||:..:|.|...::|.|.|.
 Worm   126 IDMVKTIWTPDTFFPNEKKSFFHEATSHNSFLRIDNHGNVLRSIRLTVTANCPMSLHTFPLDRQE 190

  Fly   196 CSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLR 260
            |::.:||..::.:|:::.|:.|:.:.::..:.|....|..:...:.||..||||::.|...|..:
 Worm   191 CALEVESYGYSTKDIIYHWHGTNAVTIDENVHLAHFTIGEHKHIERTISLSTGNYSRLTAYFLFK 255

  Fly   261 RRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKA 325
            |.:|::|...|.||:||||:||:|||:..||:.|||.:|||::||:.|..|.:..|||.|||||:
 Worm   256 RNIGFYLIQIYFPSSLIVVISWVSFWLNREAVQARVAIGVTTVLTMTTLMTSTNASLPKVSYVKS 320

  Fly   326 IDVWMSSCSVFVFLSLMEFAVVNNFMG-----PVAT----------------------------- 356
            :||::..|...||.||:|:|.:...|.     |.|:
 Worm   321 LDVFLGVCFFIVFASLLEYAAIGYLMKRNRSVPAASPVQYYETEEFFEIQCHPKFVRGAINYCDG 385

  Fly   357 ----------------KAMKGYSDENISDLDDLKSALQHHRES-------------------IIE 386
                            .:||.|.:.||           |||.|                   ..:
 Worm   386 VLKREASRKKSRNRRDSSMKNYQNNNI-----------HHRPSDGHVDQRIPLLSMVPMPPIPFK 439

  Fly   387 PQYDTFCHGHATAIYIDKFSRFFFPFSFFILNIVYWTTFL 426
            ||...:  |......:|.||||.||..|.|.:|||||.::
 Worm   440 PQNGAW--GKVRPAQVDLFSRFAFPIFFVIFHIVYWTYYI 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	58/194 (30%)
		Neur_chan_memb	270..>350	CDD:280999	41/79 (52%)
lgc-38	NP_001355511.1	LIC	42..476	CDD:273305	131/427 (31%)
		LGIC_ECD_GABAR_RDL-like	76..257	CDD:349809	54/181 (30%)
		Cys-loop	177..191	CDD:349809	5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45222
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820