Protein Alignment HisCl1 and Gabrr3

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001074659.1
• Gene: Gabrr3 / 328699
• MGIID: 3588203
• Length: 464
• Species: Mus musculus
• Alignment Length: 460
• Identity: 143/460 - (31%)
• Similarity: 223/460 - (48%)
• Gaps: 58/460 - (12%)

  Fly    15 IALAIYLHALEQSIQHCHC------VHGYRNNTESAELVSH--YESSLSLPDILPIPSKTYDKNR 71
            |.|.:...|:::..|.|..      :...|...:....|.|  .|..|.:.|        :|.:.
Mouse    15 ITLMLDASAIKKPHQQCLSSPKQTRIRETRMRKDDLTKVWHPKREQLLHIED--------HDFST 71

  Fly    72 APKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHS 136
            .|...|.|..|...|.|.|:|||:|.:|.:....:|...|:|.||..|...::. ...|...|..
Mouse    72 RPGFGGSPVPVGIDVQVESIDSISEVNMDFTMTFYLRHYWKDERLSFPSTTNKS-MTFDRRLLQK 135

  Fly   137 IWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIE 201
            ||.||.||.::|:...|:.::.|..|.::.|..:|:..::|:...|.|.|..:|.|||.||:.:|
Mouse   136 IWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCFMDFSRFPLDTQNCSLELE 200

  Fly   202 SLSHTVEDLVFIWNMTDPLVVNTE--IELPQLDISN-NYTTDCTIEYSTGNFTCLAIVFNLRRRL 263
            |.::..|||:..|...:. .:|||  |.|.|..|.. :.::......|||.:..|.|.|.|||.:
Mouse   201 SYAYNEEDLMLYWKHGNK-SLNTEERISLSQFFIEEFSASSGLAFYSSTGWYYRLFINFVLRRHV 264

  Fly   264 GYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDV 328
            .:.:..||.|:.|:|::||:||||...|:||||:||:|::||::|..|....|:|.||||||:||
Mouse   265 FFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTVVTGVSASMPQVSYVKAVDV 329

  Fly   329 WMSSCSVFVFLSLMEFAVVN-----------NFMGPV-------ATKAM--KGYSDENISDLDDL 373
            :|...|:|||||::|:|.||           |..|.:       |.:||  .|...::.:|:|..
Mouse   330 YMWVSSLFVFLSVIEYATVNYLTTVEEWKQLNRRGKISGMYHIDAVQAMAFDGCYHDSETDVDQT 394

  Fly   374 KSALQHHRESIIEPQYDTFC-----------HGHATAI------YIDKFSRFFFPFSFFILNIVY 421
            ..:|....:|:......:.|           .|:...|      .||.:||..||..:.|.|:.|
Mouse   395 SFSLHSEEDSMSTKFTGSPCADSSQIKRKSLGGNVGRIILENNHVIDTYSRIVFPTVYIIFNLFY 459

  Fly   422 WTTFL 426
            |..::
Mouse   460 WGIYV 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	64/197 (32%)
		Neur_chan_memb	270..>350	CDD:280999	44/90 (49%)
Gabrr3	NP_001074659.1	LIC	58..463	CDD:273305	135/414 (33%)
		Neur_chan_LBD	59..264	CDD:280998	68/214 (32%)
		Neur_chan_memb	271..460	CDD:280999	65/188 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810