Protein Alignment HisCl1 and Gabrg2

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001380704.1
• Gene: Gabrg2 / 29709
• RGDID: 61966
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 399
• Identity: 125/399 - (31%)
• Similarity: 211/399 - (52%)
• Gaps: 41/399 - (10%)

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDV 131
            ||....|.:..:||:::..:.|.|:..:|..:|.|..|||.||:|.|.||:.  |.:.:...|:.
  Rat    76 YDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKF--NSTIKVLRLNS 138

  Fly   132 DWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQIC 196
            :.:..||.||.||:|:||...|.::.||..|.:::|..:||..:||:...|.::..::|.|...|
  Rat   139 NMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSC 203

  Fly   197 SMMIESLSHTVEDLVFIWNMTDPLVVNTEI-ELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLR 260
            .:...|..:..|::|:.|..:...|.:|.. .|.|........|...::.::|::..:::.|:|.
  Rat   204 PLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLS 268

  Fly   261 RRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKA 325
            ||:||....||||..||||:||:||||..:|:|||.:||:|::||:.|.:|.:::|||.||||.|
  Rat   269 RRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTA 333

  Fly   326 IDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMKGYSDEN-----------ISDLDDLKSALQ- 378
            :|:::|.|.:|||.:|:|:..::.|:........|....:|           ..|:....:.:|
  Rat   334 MDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQM 398

  Fly   379 ----HHRESIIEPQYDT---------FC-----------HG--HATAIYIDKFSRFFFPFSFFIL 417
                |.:|...|..|:.         ||           ||  |.....:|.::|.|||.:|.:.
  Rat   399 NNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLF 463

  Fly   418 NIVYWTTFL 426
            |:|||.::|
  Rat   464 NLVYWVSYL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	55/195 (28%)
		Neur_chan_memb	270..>350	CDD:280999	41/79 (52%)
Gabrg2	NP_001380704.1	LIC	68..471	CDD:273305	124/396 (31%)
		LGIC_ECD_GABAAR_G	89..270	CDD:349801	51/182 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810