Protein Alignment HisCl1 and Gabrr1

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_058987.3
• Gene: Gabrr1 / 29694
• RGDID: 61900
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 431
• Identity: 142/431 - (32%)
• Similarity: 211/431 - (48%)
• Gaps: 77/431 - (17%)

  Fly    61 PIPSKTYDKNRAP-----KLL-------------GQPTV-VYFHVTVLSLDSINEESMTYVTDIF 106
            ||..::.|..::|     :||             |.|.: |...|.|.|||||:|..|.:...::
  Rat    60 PILKRSSDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLY 124

  Fly   107 LAQSWRDPRLRLP--ENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKT 169
            |...|:|.||..|  .|:|..:   |...:..||.||.||.::|:...|:.:..|..|.:..|..
  Rat   125 LRHYWKDERLSFPSTNNLSMTF---DGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGK 186

  Fly   170 LLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNM-TDPLVVNTEIELPQLDI 233
            :||..::|:...|.|.|..:|.|||.||:.|||.::|.:||:..|.. .|.|..:..|.|.|..|
  Rat   187 VLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLI 251

  Fly   234 SNNYTTDCTIEY-STGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVT 297
            ...:||.....| |||.:..|.|.|.|||.:.:.|..||.|:.|:|::||:||||...|:||||.
  Rat   252 QEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVP 316

  Fly   298 LGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMK-- 360
            ||:|::||::|..|....|:|.|||:||:|:::....||||||::|:|.||........|..|
  Rat   317 LGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLR 381

  Fly   361 -------------------GYSDENISDL-----------DDLKSAL-----------QHHRESI 384
                               .|||..::||           |.:...|           :..|.|.
  Rat   382 EKISCTCGLPQPRGVMLDSSYSDGEVNDLGGYMPENGEKPDRMMVQLTLASERGSPQRKSQRGSY 446

  Fly   385 IEPQYDTFCHGHATAIYIDKFSRFFFPFSFFILNIVYWTTF 425
            :..:.:|    ||    |||:||..||.::.:.|::||:.|
  Rat   447 VSMRINT----HA----IDKYSRIIFPAAYILFNLIYWSIF 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	72/217 (33%)
		Neur_chan_memb	270..>350	CDD:280999	41/79 (52%)
Gabrr1	NP_058987.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..67		2/6 (33%)
		LIC	76..479	CDD:273305	137/413 (33%)
		LGIC_ECD_GABAAR_rho	97..282	CDD:349806	67/187 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810