Protein Alignment HisCl1 and lgc-43

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001023062.1
• Gene: lgc-43 / 259591
• WormBaseID: WBGene00008076
• Length: 679
• Species: Caenorhabditis elegans
• Alignment Length: 382
• Identity: 99/382 - (25%)
• Similarity: 182/382 - (47%)
• Gaps: 33/382 - (8%)

  Fly    50 YESSLSLPDILPIPSKTYDKNRAPKLLGQ-PTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRD 113
            |.||..||   .:.|..||....|..... |..|......|.|.:.:.|.|.:..|:.:..||.|
 Worm   316 YGSSYILP---VLKSVDYDNTSVPLAFNDIPVNVAVAFNFLYLANFDSEMMEFSMDVEMEFSWID 377

  Fly   114 PRLRLPENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTL 178
              :||..|.::..||.:...:..|||||.:..|:|...||.:|.||..:.:..:..:.|..:::.
 Worm   378 --IRLVNNYTKPIRIREKPIIEQIWRPDPYIVNSKHSYFHYVSFPNIRMRITPEGLVTYTVRVSS 440

  Fly   179 VLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQLDISNNYTTDCTI 243
            |.||.|.|..||||.|.|.:.|.|::::.:.:.|.|: ::|:...::|.||:|.|:...|.:|:.
 Worm   441 VCSCFMSFCLYPHDRQECDLRISSIAYSNQYVKFHWH-SNPIKFQSKITLPELHITKIKTAECST 504

  Fly   244 EYSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLAT 308
            :....:.:||.|:|:|.|.....:...|:||.|.::.:|::.::.......|:...:|.||||..
 Worm   505 KGKLVDASCLRIIFSLERDSARFVIEKYVPSTLAMMFAWVAPYVPYNYEDVRIITPITVLLTLVQ 569

  Fly   309 QNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLME----FAVVNNFMGPVATKAMKGYSDENISD 369
            .....::.  ..||:.:||||.::...|..|||:|    .|::..      ::||...::...::
 Worm   570 MEKGDKEI--RTSYLTSIDVWFAAMKSFTVLSLLESLAVLALIKR------SRAMTKNAERAANE 626

  Fly   370 LDDLKSALQHHRESIIEPQYDTFCHGHATAIYIDKFSRFFFPFSFFILNIVYWTTFL 426
            .:......:.:|.:.:..:.|:.|...:..:::          :||    ||:..|:
 Worm   627 FERCTFEAEAYRLNRLYHRVDSICRFSSPVVFV----------AFF----VYYVLFV 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	59/195 (30%)
		Neur_chan_memb	270..>350	CDD:280999	23/83 (28%)
lgc-43	NP_001023062.1	LGIC_ECD_anion	344..523	CDD:349788	55/181 (30%)
		LGIC_TM	527..665	CDD:365787	31/159 (19%)
		TM1 helix	527..551	CDD:349850	5/23 (22%)
		TM2 helix	555..577	CDD:349850	6/21 (29%)
		TM3 helix	583..609	CDD:349850	9/25 (36%)
		TM4 helix	610..665	CDD:349850	8/74 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_129194
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820