Protein Alignment HisCl1 and GABRR1

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_002033.2
• Gene: GABRR1 / 2569
• HGNCID: 4090
• Length: 479
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 145/425 - (34%)
• Similarity: 215/425 - (50%)
• Gaps: 67/425 - (15%)

  Fly    57 PDILPIP-SKT--------YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWR 112
            |||...| :|:        :|.:..|...|....|...|.|.|||||:|..|.:...::|...|:
Human    65 PDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWK 129

  Fly   113 DPRLRLP--ENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSK 175
            |.||..|  .|:|..:   |...:..||.||.||.::|:...|:.:..|..|.:..|..:||..:
Human   130 DERLSFPSTNNLSMTF---DGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLR 191

  Fly   176 LTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNM-TDPLVVNTEIELPQLDISNNYTT 239
            :|:...|.|.|..:|.|||.||:.|||.::|.:||:..|.. .|.|..:..|.|.|..|...:||
Human   192 VTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTT 256

  Fly   240 DCTIEY-STGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSL 303
            .....| |||.:..|.|.|.|||.:.:.|..||.|:.|:|::||:||||...|:||||.||:|::
Human   257 TKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTV 321

  Fly   304 LTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVN-------------------- 348
            ||::|..|....|:|.|||:||:|:::....||||||::|:|.||
Human   322 LTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCT 386

  Fly   349 NFMGPVATKAMKG-YSDENISDLDDL--------------------KSALQH--HRESIIEPQYD 390
            :.:.|..|..:.| |||..::|||:.                    :|:.|.  .|.|.:..:.|
Human   387 SGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRID 451

  Fly   391 TFCHGHATAIYIDKFSRFFFPFSFFILNIVYWTTF 425
            |    ||    |||:||..||.::.:.|::||:.|
Human   452 T----HA----IDKYSRIIFPAAYILFNLIYWSIF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	69/198 (35%)
		Neur_chan_memb	270..>350	CDD:280999	41/99 (41%)
GABRR1	NP_002033.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..55
		LIC	75..478	CDD:273305	139/413 (34%)
		Neur_chan_LBD	76..281	CDD:280998	70/207 (34%)
		Neur_chan_memb	288..475	CDD:280999	66/194 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810